Host factors facilitating SARS‐CoV‐2 virus infection and replication in the lungs

S Boutin, D Hildebrand, S Boulant, M Kreuter… - Cellular and Molecular …, 2021 - Springer
SARS-CoV-2 is the virus causing the major pandemic facing the world today. Although,
SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic …

[HTML][HTML] SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections

F Cyprian, MU Sohail, I Abdelhafez, S Salman… - International Journal of …, 2021 - Elsevier
By the beginning of 2020, infection caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an …

Infections of the lung: a predictive, preventive and personalized perspective through the lens of evolution, the emergence of SARS-CoV-2 and its pathogenesis

P Ahluwalia, M Ahluwalia, K Vaibhav, A Mondal… - EPMA Journal, 2020 - Springer
The long evolutionary battle between humans and pathogens has played an important role
in shaping the current network of host-pathogen interactions. Each organ brings new …

The impact of infection with COVID-19 on the respiratory microbiome: A narrative review

T Zhu, J Jin, M Chen, Y Chen - Virulence, 2022 - Taylor & Francis
ABSTRACT Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has affected
millions of individuals with various implications. Consistent with the crucial role of the …

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of …

H Chu, JFW Chan, Y Wang, TTT Yuen… - Clinical Infectious …, 2020 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an
emerging coronavirus that has resulted in more than 2 000 000 laboratory-confirmed cases …

Unraveling the interconnection patterns across lung microbiome, respiratory diseases, and COVID-19

E Stavropoulou, K Kantartzi, C Tsigalou… - Frontiers in cellular …, 2021 - frontiersin.org
Albeit the lungs were thought to be sterile, recent scientific data reported a microbial
microbiota in the lungs of healthy individuals. Apparently, new developments in …

SARS-CoV-2 isolates show impaired replication in human immune cells but differential ability to replicate and induce innate immunity in lung epithelial cells

M Jiang, P Kolehmainen, L Kakkola… - Microbiology …, 2021 - Am Soc Microbiol
The primary target organ of coronavirus disease 2019 (COVID-19) infection is the respiratory
tract. Currently, there is limited information on the ability of severe acute respiratory …

Mechanisms of infection by SARS-CoV-2, inflammation and potential links with the microbiome

MM Aguirre Garcia, J Mancilla-Galindo… - Future …, 2021 - Taylor & Francis
The pandemic SARS coronavirus 2 utilizes efficient mechanisms to establish infection and
evade the immune system. Established infection leads to severe inflammation in susceptible …

Potential associations between microbiome and COVID-19

H Wang, H Wang, Y Sun, Z Ren, W Zhu, A Li… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has plunged the world into a major crisis …

Role of the Microbiome in the Pathogenesis of COVID-19

R De, S Dutta - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The ongoing pandemic coronavirus disease COVID-19 is caused by the highly contagious
single-stranded RNA virus, SARS-coronavirus 2 (SARS-CoV-2), which has a high rate of …