Fixed dosage regimens for anti-type I interferon receptor (IFNAR) antibodies

B Higgs, Y Yao, B Wang, L Roskos, L Chang - US Patent 9,493,570, 2016 - Google Patents
The disclosure provides methods for treating a subject having a type IIFN-mediated disease
or disorder comprising administration of a fixed does of an anti-interferon alpha receptor …

Anti-interferon gamma antibodies and uses thereof

CL Ku, HP Shih, CH Lin, JY Ding, JY Huang… - US Patent …, 2021 - Google Patents
Provided is an anti-INF-y antibody. Also provided are a composition comprising the antibody
and a pharmaceutical application of the antibody in treating IFN-Y mediated syndrome …

Anti-interferon-α antibodies

A Chuntharapai, JK Kim, LG Presta… - US Patent 7,910,707, 2011 - Google Patents
5.780, 027 A 7, 1998 Maroun bodies with broad reactivity against various IFN-C. subtypes.
5,789,551 A 8, 1998 Pestka The invention further relates to the use of such anti-IFN-O …

Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors

AA Welcher, HT Chute, H Huang - US Patent 7,335,743, 2008 - Google Patents
This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-
Y) and methods for treat ing IFN-Y mediated diseases by administering a pharmaceu tically …

Interferon alpha receptor I antibodies and their use

JM Cardarelli, A Witte, M Srinivasan - US Patent 8,460,668, 2013 - Google Patents
2003, 0166228 A1 9/2003 Chuntharapai et al. 2004, OO67888 A1 4/2004 Tovey et al.
2005/O152901 A1 7/2005 Pickford et al. 2005/0208041 A1 9, 2005 Cardarelli et al …

Nucleic acid molecules that encode human anti-IFN-gamma neutralizing antibodies as selective IFN-gamma pathway inhibitors

AA Welcher, HT Chute, YSL Li, H Huang - US Patent 8,202,976, 2012 - Google Patents
This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-
Y) and methods for treating IFN-Y mediated diseases by administering a pharmaceuti cally …

Interferon receptor 1 antibodies and their uses

JM Cardarelli, A Witte, M Srinivasan - US Patent 9,453,077, 2016 - Google Patents
The present invention provides isolated human monoclonal antibodies that bind to IFNAR-1
and that are capable of inhibiting the biological activity of Type I interferons …

Humanized antibodies to interferon alpha receptor-1 (IFNAR-1)

JM Cardarelli, TT Chen, D King, CR Bebbington… - US Patent …, 2011 - Google Patents
Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based
compositions and molecules, are disclosed. Also disclosed are pharmaceutical …

Anti-interferon-α antibodies

A Chuntharapai, JK Kim, LG Presta… - US Patent 7,087,726, 2006 - Google Patents
US7087726B2 - Anti-interferon-α antibodies - Google Patents US7087726B2 - Anti-interferon-α
antibodies - Google Patents Anti-interferon-α antibodies Download PDF Info Publication …

Humanized antibodies to interferon alpha receptor-1 (IFNAR-1)

JM Cardarelli, TT Chen, DJ King… - US Patent …, 2009 - Google Patents
Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based
compositions and molecules, are disclosed. Also disclosed are pharmaceutical …