Non-invasive Vagus nerve stimulation in cerebral stroke: current status and future perspectives

L Li, D Wang, H Pan, L Huang, X Sun, C He… - Frontiers in …, 2022 - frontiersin.org
Stroke poses a serious threat to human health and burdens both society and the healthcare
system. Standard rehabilitative therapies may not be effective in improving functions after …

Vagus nerve stimulation in ischemic stroke: old wine in a new bottle

PY Cai, A Bodhit, R Derequito, S Ansari… - Frontiers in …, 2014 - frontiersin.org
Vagus nerve stimulation (VNS) is currently Food and Drug Administration-approved for
treatment of both medically refractory partial-onset seizures and severe, recurrent refractory …

Research advances in the application of vagus nerve electrical stimulation in ischemic stroke

K Cheng, Z Wang, J Bai, J Xiong, J Chen… - Frontiers in …, 2022 - frontiersin.org
Stroke seriously endangers human well-being and brings a severe burden to family and
society. Different post-stroke dysfunctions result in an impaired ability to perform activities of …

Transcutaneous vagus nerve stimulation combined with robotic rehabilitation improves upper limb function after stroke

F Capone, S Miccinilli, G Pellegrino, L Zollo… - Neural …, 2017 - Wiley Online Library
The efficacy of standard rehabilitative therapy for improving upper limb functions after stroke
is limited; thus, alternative strategies are needed. Vagus nerve stimulation (VNS) paired with …

Efficacy and safety of vagus nerve stimulation in stroke rehabilitation: a systematic review and meta-analysis

R Ananda, MHB Roslan, LL Wong, NP Botross… - Cerebrovascular …, 2023 - karger.com
Introduction: Recent randomized controlled trials (RCTs) have assessed the role of vagus
nerve stimulation (VNS) when paired with standard rehabilitation in stroke patients. This …

NOn-invasive Vagus nerve stimulation in acute Ischemic Stroke (NOVIS): a study protocol for a randomized clinical trial

A van der Meij, MAA van Walderveen, ND Kruyt… - Trials, 2020 - Springer
Background Secondary damage due to neurochemical and inflammatory changes in the
penumbra in the first days after ischemic stroke contributes substantially to poor clinical …

[HTML][HTML] Assessment of safety and feasibility of non-invasive vagus nerve stimulation for treatment of acute stroke

EM Arsava, MA Topcuoglu, I Ay, AO Ozdemir… - Brain stimulation, 2022 - Elsevier
Background Non-invasive vagus nerve stimulation (nVNS) using a hand-held stimulator
placed on the neck is an FDA-approved treatment for primary headache disorders. The …

Vagus nerve stimulation as a promising adjunctive treatment for ischemic stroke

J Ma, P Qiao, Q Li, Y Wang, L Zhang, LJ Yan… - Neurochemistry …, 2019 - Elsevier
Abstract The Food and Drug Administration has approved vagus-nerve stimulation (VNS) for
the treatment of patients with epilepsy, depression, and headache. By targeting diverse …

Transcutaneous vagus nerve stimulation (tVNS) in stroke: the evidence, challenges and future directions

SS Baig, M Kamarova, A Ali, L Su, J Dawson… - Autonomic …, 2022 - Elsevier
Stroke is one of the leading causes of death and disability globally. A significant proportion
of stroke survivors are left with long term neurological deficits that have a detrimental effect …

Targeted vagus nerve stimulation for rehabilitation after stroke

ND Engineer, TJ Kimberley, CN Prudente… - Frontiers in …, 2019 - frontiersin.org
Stroke is a leading cause of disability worldwide, and in approximately 60% of individuals,
upper limb deficits persist 6 months after stroke. These deficits adversely affect the functional …