Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production,
support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate …

Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Through their many and varied metabolic functions, mitochondria power life. Paradoxically,
mitochondria also have a central role in apoptotic cell death. Upon induction of …

Mitochondria are well known as the centre of energy metabolism in eukaryotic cells.
However, they can not only generate ATP through the tricarboxylic acid cycle and oxidative …

Mitochondrial function is key for maintaining cellular health, while mitochondrial failure is
associated with various pathologies, including inherited metabolic disorders and age …

Mitochondria are the energy producing dynamic double-membraned organelles essential
for cellular and organismal survival. A multitude of intra-and extra-cellular signals involved in …

Mitochondria, the main energy hub of the cell, are highly dynamic organelles, playing
essential roles in fundamental cellular processes. Mitochondrial function impinges on …

The mitochondrion has long been known both as a chemical powerplant and as a cellular
compartment housing various biosynthetic pathways. However, studies on the function of …

Mitochondria are the key energy-producing organelles and cellular source of reactive
species. They are responsible for managing cell life and death by a balanced homeostasis …

• Introduction• Mitochondria and cell death• Mitochondrial outer membrane permeabilization
(MOMP): point of no return‐MOMP by BCL‐2 family proteins‐MOMP by permeability …