Background Digestive malignancies, especially pancreatic cancer (PC), gastric cancer (GC),
and colorectal cancer (CRC), still occur at persistently high rates, and disease progression …

Natural killer (NK) cell activity is influenced by a complex integration of signaling pathways
activated downstream of both activating and inhibitory surface receptors. The tumor …

Background Natural killer (NK) cells play a key role in non-specific immune response in
different cancers, including pancreatic cancer. However the anti-tumor effect of NK cells …

Background: Tumor-infiltrating natural killer (NK) cells (TINKs) are crucial immune cells in
tumor defense, and might be related to tumor prognosis. However, the results were …

Abstract Background and Aim We aimed to measure the natural killer (NK) cell activity and
pro‐inflammatory cytokine levels in the peripheral blood of pancreatic cancer patients and …

The clinical outcome of colorectal cancer (CRC) is associated with the immune response;
thus, these tumors could be responsive to different immune therapy approaches. Natural …

Defects in natural killer (NK) cell functions are necessary for tumor immune escape, but their
underlying regulatory mechanisms in human cancers remain largely unknown. Here we …

Natural Killer (NK) cells are effector lymphocytes involved in tumor immunosurveillance,
however, the specific mechanism in hepatocellular carcinoma (HCC) has not been well …

Despite NK cells being originally identified because of their ability to kill tumor cells in vitro,
only limited information is available on NK cells infiltration of malignant tumors, especially in …

Purpose: Tumor infiltrating T lymphocytes in colorectal cancer (CRC) have prognostic
impact, but the role of natural killer (NK) cells in CRC tissue is unclear. The contribution of …