Tamoxifen (TMX), commonly used in complementary therapy for breast cancer, also displays
known effects on the structure and function of biological membranes. This work presents an …

The anticancer drug tamoxifen and its primary metabolite 4-hydroxytamoxifen tend to
accumulate in membranes due to its strong hydrophobic character. Thus, in this work we …

The temperature-and concentration-induced effects of tamoxifen (TAM) on dipalmitoyl
phosphatidylcholine (DPPC) model membranes were investigated by the Fourier transform …

The perturbation of the lipid bilayer structure by tamoxifen may contribute to its multiple
mechanisms of anticancer action not related to estrogen receptors. This study evaluates the …

The interactions of tamoxifen with lipid bilayers of model and native membranes were
investigated by fluorescence polarization of 1, 6-diphenyl-1, 3, 5-hexatriene (DPH) and by …

Purpose The purpose of this study was to inspect the interactions between an anti-breast
cancer, TAM, with model of lipid membranes composed of either zwitterionic DPPC LUVs or …

Tamoxifen (TAM) is a non-steroidal antiestrogen drug, which is widely used to prevent and
treat breast, liver, pancreas and brain cancers. The present work investigates, in detail, the …

The effects of hydroxytamoxifen (OHTAM) on lipid organization of pure phospholipid
liposomes, native sarcoplasmic reticulum (SR) membranes and liposomes of SR lipids were …

Interactions of the hydrophobic anticancer drug tamoxifen (TAM) with lipid model
membranes were studied using calcein-encapsulated vesicle leakage, attenuated total …

There are contradictory results in the literature relating to the effect oftamoxifen on
membrane fluidity. The present work investigates the effect oftamoxifen on membrane …