The increasing antibiotic resistance of Helicobacter pylori primarily driven by genetic
mutations poses a significant clinical challenge. Although previous research has suggested …

The microaerophilic gastric pathogen Helicobacter pylori is exposed to oxidative stress
originating from the aerobic environment, the oxidative burst of phagocytes and the …

Background Helicobacter pylori's Fur regulatory protein controls transcription of dozens of
genes in response to iron availability, acidity and oxidative stress, and affects the vigor of …

Helicobacter pylori is a significant human pathogen that has adapted to survive the many
stresses found within the gastric environment. Superoxide Dismutase (SodB) is an important …

Metronidazole (Mtz) is a prodrug that is converted to its active form when its nitro group is
reduced and superoxide radicals are generated. The superoxide radicals are directly toxic to …

Ferric uptake regulator (Fur) of Helicobacter pylori is a global regulator that is important for
bacterial colonization and survival within the gastric mucosa. H. pylori Fur (Hp Fur) is unique …

In Helicobacter pylori, the ferric uptake regulator (Fur) has evolved additional regulatory
functions not seen in other bacteria; it can repress and activate different groups of genes in …

Helicobacter pylori, a pathogenic bacterium that colonizes in the human stomach, harbors
DNA repair genes to counter the gastric environment during chronic infection. In addition, H …

In this study, we systematically examined in vitro frequencies and spectra of the
spontaneous mutations in Helicobacter pylori that confer resistance to clarithromycin (Clar) …

The ferric uptake regulator (Fur) of H elicobacter pylori is a global regulator that is important
for colonization and survival within the gastric mucosa. H. pylori Fur is unique in its ability to …