This article provides a comprehensive review of currently available treatment options for
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …

In recent years, carbapenem resistance among Enterobacteriaceae has dramatically
increased and represents an important threat to global health. The optimal therapeutic …

Background Carbapenem resistance is defined as in vitro non-susceptibility to any
carbapenem and/or documented production of a carbapenemase. This feature has rapidly …

The emergence of carbapenem resistance in Enterobacteriaceae is an important threat to
global health. Reported outcomes of infections with carbapenem-resistant …

Carbapenems are considered as last-resort antibiotics for the treatment of infections caused
by multidrug-resistant Gram-negative bacteria. With the increasing use of carbapenems in …

Carbapenem-resistant Enterobacterales (CRE) are a growing threat to human health
worldwide. CRE often carry multiple resistance genes that limit treatment options and …

We sought to evaluate the effectiveness of the antibiotic treatment administered for infections
caused by carbapenemase-producing Enterobacteriaceae. The PubMed and Scopus …

Infections due to multidrug-resistant Enterobacteriaceae have become major international
public health problem due to the inadequate treatment options and the historically lagged …

Introduction: For the past three decades, carbapenems played a central role in our antibiotic
armamentarium, trusted to effectively treat infections caused by drug-resistant bacteria. The …

The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the
importance of effective antibiotics to maintain the safety of our health care system. Clinicians …