M2 macrophage-derived exosomes carry microRNA-148a to alleviate myocardial ischemia/reperfusion injury via inhibiting TXNIP and the TLR4/NF-κB/NLRP3 …
Y Dai, S Wang, S Chang, D Ren, S Shali, C Li… - Journal of molecular and …, 2020 - Elsevier
Background Reperfusion may cause injuries to the myocardium in ischemia situation.
Emerging studies suggest that exosomes may serve as key mediators in myocardial …
Emerging studies suggest that exosomes may serve as key mediators in myocardial …
M2 macrophage-derived exosomes carry miR-1271-5p to alleviate cardiac injury in acute myocardial infarction through down-regulating SOX6
R Long, L Gao, Y Li, G Li, P Qin, Z Wei, D Li, C Qian… - Molecular …, 2021 - Elsevier
Background Emerging evidence has indicated that exosomes serve as key regulators in
acute myocardial infarction (AMI). This study was determined to investigate the effect of M2 …
acute myocardial infarction (AMI). This study was determined to investigate the effect of M2 …
M1-like macrophage-derived exosomes suppress angiogenesis and exacerbate cardiac dysfunction in a myocardial infarction microenvironment
S Liu, J Chen, J Shi, W Zhou, L Wang, W Fang… - Basic research in …, 2020 - Springer
The roles and the underlying mechanisms of M1-type macrophages in angiogenesis and
postmyocardial infarction (MI) cardiac repair have remained unclear. In this study, we …
postmyocardial infarction (MI) cardiac repair have remained unclear. In this study, we …
[HTML][HTML] Mesenchymal stem cell-derived exosomal microRNA-182-5p alleviates myocardial ischemia/reperfusion injury by targeting GSDMD in mice
R Yue, S Lu, Y Luo, J Zeng, H Liang, D Qin… - Cell death …, 2022 - nature.com
Recent evidence indicates that exosomes derived from mesenchymal stem cells (MSCs)
confer protective effects against myocardial ischemia/reperfusion (I/R) injury. Exosomes are …
confer protective effects against myocardial ischemia/reperfusion (I/R) injury. Exosomes are …
Exosomal microRNA-98-5p from hypoxic bone marrow mesenchymal stem cells inhibits myocardial ischemia–reperfusion injury by reducing TLR4 and activating the …
L Zhang, Q Wei, X Liu, T Zhang, S Wang, L Zhou… - International …, 2021 - Elsevier
Objective MicroRNAs (miRNAs) are essential biomarkers during development of human
diseases. We aimed to explore the role of hypoxia-induced bone marrow mesenchymal …
diseases. We aimed to explore the role of hypoxia-induced bone marrow mesenchymal …
Bone marrow mesenchymal stem cell-derived exosomal miRNA-29c decreases cardiac ischemia/reperfusion injury through inhibition of excessive autophagy via the …
T Li, J Gu, O Yang, J Wang, Y Wang, J Kong - Circulation Journal, 2020 - jstage.jst.go.jp
Background: Cardiac ischemia/reperfusion (I/R) injury will cause a large amount of
cardiomyocyte loss and cascade reactions such as apoptosis, mitochondrial dysfunction …
cardiomyocyte loss and cascade reactions such as apoptosis, mitochondrial dysfunction …
Human umbilical cord mesenchymal stem cells-derived exosomes transfers microRNA-19a to protect cardiomyocytes from acute myocardial infarction by targeting …
L Huang, L Yang, Y Ding, X Jiang, Z Xia, Z You - Cell Cycle, 2020 - Taylor & Francis
Exosomes secreted by human umbilical cord mesenchymal stem cells (hucMSCs) protect
cardiomyocytes from anoxia-reoxygenation injury. But the mechanism of hucMSC-exo …
cardiomyocytes from anoxia-reoxygenation injury. But the mechanism of hucMSC-exo …
Exosomes derived from miR‐146a‐modified adipose‐derived stem cells attenuate acute myocardial infarction− induced myocardial damage via downregulation of …
J Pan, M Alimujiang, Q Chen, H Shi… - Journal of cellular …, 2019 - Wiley Online Library
Multiple studies demonstrated that early growth response factor 1 (EGR1) induces
myocardial damage after acute myocardial infarction (AMI). Recent evidence indicates that …
myocardial damage after acute myocardial infarction (AMI). Recent evidence indicates that …
[HTML][HTML] miR-93-5p-containing exosomes treatment attenuates acute myocardial infarction-induced myocardial damage
J Liu, M Jiang, S Deng, J Lu, H Huang, Y Zhang… - … Therapy-Nucleic Acids, 2018 - cell.com
Adipose-derived stromal cells (ADSCs) have been considered as an attractive therapeutic
tool. Accumulating evidence indicates that the healing effects of ADSCs are mainly related to …
tool. Accumulating evidence indicates that the healing effects of ADSCs are mainly related to …
[PDF][PDF] MicroRNA-338 in MSCs-derived exosomes inhibits cardiomyocyte apoptosis in myocardial infarction.
DL Fu, H Jiang, CY Li, T Gao, MR Liu… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: Myocardial infarction (MI) is caused by myocardial ischemia and hypoxia,
which causes irreversible damage to the myocardium and seriously endangers human …
which causes irreversible damage to the myocardium and seriously endangers human …
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