Mucus, the continuously secreted viscoelastic gel coating the respiratory tract, poses a major
barrier to sustained and/or targeted drug delivery to the airways. Mucus is primarily …

Airway mucus is a complex viscoelastic gel that provides a defensive physical barrier and
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …

In the lung, the airway epithelium produces secreted and tethered mucin biopolymers to
form a mucus hydrogel layer and a surface-attached polymer brush layer. These layers work …

Mucus covers all wet epithelia and acts as a protective barrier. In the airways of the lungs,
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …

Chronic lung diseases such as cystic fibrosis, chronic bronchitis, and asthma are
characterized by hypersecretion and poor clearance of mucus, which are associated with …

As asthma worsens, occlusion of airways with mucus significantly contributes to airflow
obstruction and reduced lung function. Recent evidence from clinical studies has shown …

Mucus is a biological hydrogel that coats every wet epithelial surface of the body, including
the respiratory tract. Within the body, mucus serves as a barrier: a mesh network made of …

The respiratory tract epithelium is hydrated by a mucous layer, which forms a protective
barrier for the defense against sometimes life-threatening foreign particles, including …

Mucus plays a critical role in the innate immunity of the airways acting as the body's first line
of defense against pathogens. Mucus is a complex gel and much is still unknown regarding …

The respiratory epithelium is lined by mucus, a gel consisting of water, ions, proteins, and
macromolecules. The major macromolecular components of mucus are the mucin …