Chronic unexplained gastrointestinal symptoms impact more than 1 in 5 Americans and their
families; these disorders include the irritable bowel syndrome (IBS) and functional …

Gastrointestinal conditions may be broadly classified into two: organic and functional
disease, with functional disorders accounting for the majority of patients with chronic …

Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal (GI) tract
characterized by pain or discomfort from the lower abdominal region, which is associated …

BACKGROUND: Subtle histopathologic features such as eosinophilia and increased mast
cells have been observed in functional gastrointestinal disorders (FGIDs), including …

This review presents studies that support an inflammation-immunological model for the
pathogenesis of post-infectious irritable bowel syndrome (IBS), and highlights recent studies …

Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so
named because a defined pathophysiology in terms of structural or biochemical pathways is …

AIM The aim of the present study was to investigate whether coexisting IBS is also
associated with symptom pattern or pathophysiology in FD. METHODS In 309 consecutive …

Histopathologic data demonstrate low-grade mucosal inflammation in a subset of patients
with irritable bowel syndrome (IBS). This inflammatory infiltrate is mainly represented by …

Abstract Background and Summary: Traditionally, functional gastrointestinal disorders
(FGID), including functional dyspepsia or irritable bowel syndrome (IBS), are defined by …

Irritable bowel syndrome (IBS) is a clinical descriptor rather than a diagnosis with an
established underlying etiology. Definitions of IBS focus on the presence of pain and the …