Strategies to reduce use of antidepressants

T Kendrick - British Journal of Clinical Pharmacology, 2021 - Wiley Online Library
Antidepressant prescribing has increased year on year since the introduction of the selective
serotonin reuptake inhibitors (SSRIs) in the 1980s. More than 10% of adults in England are …

Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop

M Horowitz, M Wilcock - Drug and Therapeutics Bulletin, 2022 - dtb.bmj.com
In England, the prescribing of antidepressants, primarily the newer generation
antidepressant classes, has steadily increased over recent years. There is ongoing debate …

Antidepressant use in clinical practice: efficacy v. effectiveness

J Donoghue, TR Hylan - The British Journal of Psychiatry, 2001 - cambridge.org
BackgroundAlthough the efficacy of antidepressants has been demonstrated in randomised,
controlled clinical trials, it is how an antidepressant is used in clinical practice that …

Guidelines for treating depressive illness with antidepressants: a statement from the British Association for Psychopharmacology

SA Montgomery, P Bebbington… - Journal of …, 1993 - journals.sagepub.com
Depression is a common illness which affects some 3% of the population per year. At least
25% of those with marked depression do not consult their general practitioner and in half of …

Longitudinal patterns of antidepressant prescribing in primary care in the UK: comparison with treatment guidelines

RL Dunn, JM Donoghue… - Journal of …, 1999 - journals.sagepub.com
The objective of this study was to determine whether patients beginning therapy on the most
common tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) …

The treatment of depression in UK general practice: selective serotonin reuptake inhibitors and tricyclic antidepressants compared

RA Lawrenson, F Tyrer, RB Newson… - Journal of affective …, 2000 - Elsevier
Background: Antidepressants are commonly prescribed by general practitioners as
treatment for depression. Controversy exists as to the effectiveness in everyday use of the …

Selective serotonin reuptake inhibitors have broadened the utilisation of antidepressant treatment in accordance with recommendations: findings from a Swedish …

G Isacsson, G Boëthius, S Henriksson, JK Jones… - Journal of Affective …, 1999 - Elsevier
Background: With the advent of the selective serotonin reuptake inhibitors (SSRIs), the use
of antidepressants has increased drastically in Sweden. The use of tricyclic antidepressants …

Indications for and outcome of antidepressant medication in a general population: a prescription database and medical record study, in Jämtland county, Sweden …

S Henriksson, G Boëthius, J Håkansson… - Acta Psychiatrica …, 2003 - Wiley Online Library
Objective: To examine the indications for prescribing antidepressants and the clinical
outcome when they are prescribed for the treatment of depression, and compare tricyclic …

Reviewing long-term antidepressants can reduce drug burden: a prospective observational cohort study

CF Johnson, HJ Macdonald, P Atkinson… - British Journal of …, 2012 - bjgp.org
Background Antidepressant prescribing continues to rise. Contributing factors are increased
long-term prescribing and possibly the use of higher selective serotonin re-uptake inhibitor …

Staying on, and coming off, antidepressants: the experiences of 752 UK adults

J Read, A Gee, J Diggle, H Butler - Addictive Behaviors, 2019 - Elsevier
Introduction Prescription rates for antidepressants (ADs) are high and continue to increase,
despite evidence of significant adverse effects, including withdrawal symptoms, and …