Tuberculosis (TB) is a lethal disease and remains one of the top ten causes of mortality by
an infectious disease worldwide. It can also result in significant morbidity related to …

Tuberculosis (TB) is one of the leading causes of death worldwide, consistently threatening
public health. Conventional tuberculosis treatment requires a long-term treatment regimen …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality in humans worldwide. Currently, the standard treatment for TB …

Tuberculosis (TB) is one of the leading causes of mortality and morbidity, particularly in
developing countries, presenting a major threat to the public health. The currently …

Background: Tuberculosis (TB) ranks alongside the human immunodeficiency virus (HIV) as
cause of death due to an infectious disease. Recently, host-targeted therapies (HDT) have …

Tuberculosis (TB) maintains its infamous status regarding its detrimental effect on global
health, causing the highest mortality by a single infectious agent. The presence of resistance …

Abstract Treatment of multidrug-resistant tuberculosis (MDR-TB) is extremely challenging
due to the virulence of the etiologic strains of Mycobacterium tuberculosis (M. tb), the …

Abstract Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but
has limited efficacy against pulmonary TB disease development and modest protection …

The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …

New therapeutics to augment current approaches and shorten treatment duration are of
critical importance for combating tuberculosis (TB), especially those with novel mechanisms …