Can focal therapy successfully control prostate cancer? Also, if so, which patients should be
considered eligible? With limited data available from relatively few patients, these questions …

PURPOSE: Based on contemporary epidemiological and pathological characteristics of
prostate cancer we explain the rationale for and concerns about focal therapy for low risk …

CONTEXT: A significant proportion of patients diagnosed with prostate cancer have well-
differentiated, low-volume tumors at minimal risk of impacting their quality of life or longevity …

For men residing within the United States, prostate cancer is second only to lung cancer in
cancer mortality and second in incidence to nonmelanomatous skin cancers. The …

The treatment paradigm for small-volume, low-grade unifocal or unilateral prostate cancer is
shifting from a radical, whole-gland approach toward organ-sparing, focal ablation. The …

Focal ablative therapy may be reasonable for some patients with prostate cancer; selection
factors include a variety of clinical and pathologic factors in combination with informed …

What's known on the subject? and What does the study add? Much of our understanding of
the pathological basis of prostate cancer comes from our analysis of radical prostatectomy …

Background Focal therapy is being offered as a viable alternative for men with localised
prostate cancer (PCa), but it is unclear which men may be suitable. Objective To determine …

Purpose: To establish a consensus in relation to case selection, conduct of therapy, and
outcomes that are associated with focal therapy for men with localized prostate cancer …

Purpose: Optimization of prostate biopsy requires addressing the shortcomings of standard
systematic transrectal ultrasound guided biopsy, including false-negative rates, incorrect risk …