Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

IRA Mackenzie, M Neumann - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The past decade has seen the discovery of several new FTD‐causing genetic …

neuropathology of non‐tau frontotemporal lobar degeneration

M Neumann, IRA Mackenzie - Neuropathology and applied …, 2019 - Wiley Online Library
Frontotemporal dementia (FTD) is a heterogeneous clinical syndrome associated with
frontotemporal lobar degeneration (FTLD) as a relatively consistent neuropathological …

The molecular basis of frontotemporal dementia

M Neumann, M Tolnay, IRA Mackenzie - Expert reviews in molecular …, 2009 - cambridge.org
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. Familial FTD has been linked to mutations in several genes, including those encoding …

Advances in understanding the molecular basis of frontotemporal dementia

R Rademakers, M Neumann… - Nature Reviews Neurology, 2012 - nature.com
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. Until recently, the underlying cause was known in only a minority of cases that were …

Frontotemporal dementia

J Deleon, BL Miller - Handbook of clinical neurology, 2018 - Elsevier
Frontotemporal dementia (FTD) is a neurodegenerative disorder characterized by
progressive changes in behavior, personality, and language with involvement of the frontal …

Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias

RT Mott, DW Dickson, JQ Trojanowski… - Journal of …, 2005 - academic.oup.com
The frontotemporal dementias (FTDs) are a heterogeneous group of neurodegenerative
disorders that are characterized clinically by dementia, personality changes, language …

Frontotemporal dementia: implications for understanding Alzheimer disease

M Goedert, B Ghetti… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Frontotemporal dementia (FTD) comprises a group of behavioral, language, and movement
disorders. On the basis of the nature of the characteristic protein inclusions, frontotemporal …

The clinical spectrum of sporadic and familial forms of frontotemporal dementia

IOC Woollacott, JD Rohrer - Journal of neurochemistry, 2016 - Wiley Online Library
The term frontotemporal dementia (FTD) describes a clinically, genetically and
pathologically diverse group of neurodegenerative disorders. Symptoms of FTD can present …

Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine

DJ Irwin, NJ Cairns, M Grossman, CT McMillan… - Acta …, 2015 - Springer
Frontotemporal lobar degeneration (FTLD) comprises two main classes of
neurodegenerative diseases characterized by neuronal/glial proteinaceous inclusions (ie …

An update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations

T Lashley, JD Rohrer, S Mead… - Neuropathology and …, 2015 - Wiley Online Library
The development of our understanding of frontotemporal dementia (FTD) has gathered pace
over the last 10 years. After taking a back seat to A lzheimer's disease for many years FTD …