HIV-1 derived lentiviral vector is an efficient transporter for delivering desired genetic
materials into the targeted cells among many viral vectors. Genetic material transduced by …

Lentiviral vectors are a powerful tool for gene transfer into target cells in vitro and in vivo.
However, there are concerns about safety with regard to their use in gene transfer protocols …

Lentiviruses are powerful tools for gene delivery and have been widely used for the
dissection of gene functions in both replicating and quiescent cells. Recently, lentiviruses …

Gene vehicles derived from lentiviruses have become highly esteemed tools for gene
transfer and genomic insertion in a wealth of cell types both in vivo and ex vivo. However …

HIV-1 derived vectors are among the most efficient for gene transduction in mammalian
tissues. As the parent virus, they carry out vector genome insertion into the host cell …

Lentiviral vectors (LVs) offer the advantages of a large packaging capacity, broad cell
tropism or specific cell-type targeting through pseudotyping, and long-term expression from …

Lentiviral vectors are among the most efficient gene transfer tools for dividing and non-
dividing cells. However, insertional mutagenesis has been observed in clinical trials with …

Lentivirus-derived vectors are among the most promising viral vectors for gene therapy
currently available, but their use in clinical practice is limited by the associated risk of …

Integrase-defective lentiviral vectors (IDLVs) represent an attractive platform for vaccine
development as a result of the ability to induce persistent humoral-and cellular-mediated …

Genetic immunization with lentiviral vectors is under evaluation as a means for induction of
sustained immune response. Lentiviral vectors showed reduced antivector immune …