Metal complexes as diagnostic tools

DE Reichert, JS Lewis, CJ Anderson - Coordination Chemistry Reviews, 1999 - Elsevier
This review summarizes some of the developments of metal complexes and metal-complex-
bioconjugates for the diagnosis of disease states that have occurred over the past 10 years …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Supramolecular coordination complexes as diagnostic and therapeutic agents

G Yu, M Jiang, F Huang, X Chen - Current opinion in chemical biology, 2021 - Elsevier
The metal-based drugs represented by cisplatin, carboplatin, and oxaliplatin, prevail in
cancer treatment, whereas new therapeutics are extremely slow to step into the clinic. Poor …

Overview of transition metal and lanthanide complexes as diagnostic tools

L Thunus, R Lejeune - Coordination chemistry reviews, 1999 - Elsevier
This review presents an overview of various elements used in the preparation of imaging
contrast agents. After a brief introduction to the history of the development of labelling …

Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

[图书][B] Medicinal applications of coordination chemistry

CJ Jones, JR Thornback - 2007 - books.google.com
Metals in pharmaceuticals have played an increasingly important role in medicine over the
last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal …

Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions

V Carroll, DW Demoin, TJ Hoffman, SS Jurisson - Radiochimica acta, 2012 - degruyter.com
Radiometals play an important role in diagnostic and therapeutic radiopharmaceuticals. This
field of radiochemistry is multidisciplinary, involving radiometal production, separation of the …

Metal complexes for therapeutic applications

J Karges, RW Stokes, SM Cohen - Trends in chemistry, 2021 - cell.com
Metal complexes have been widely used for applications in the chemical and physical
sciences due to their unique electronic and stereochemical properties. For decades the use …

Metal complexes in medicinal chemistry: new vistas and challenges in drug design

KH Thompson, C Orvig - Dalton transactions, 2006 - pubs.rsc.org
An overview is presented of selected metal-based pharmaceuticals, either diagnostic or
therapeutic, with emphasis on specific attributes and in vivo interactions of these compounds …

Nano-functionalization of metal complexes for molecular imaging and anticancer therapy

CR Maldonado, L Salassa, N Gomez-Blanco… - Coordination Chemistry …, 2013 - Elsevier
Recently, there has been a growing interest in functionalizing metal complexes with
biomolecules and nanomaterials for molecular imaging and anticancer therapy applications …