X-linked dystonia-parkinsonism is a neurodegenerative disorder caused by a founder
retrotransposon insertion, in which a polymorphic hexanucleotide repeat accounts for~ 50 …

While many genetic causes of movement disorders have been identified, modifiers of
disease expression are largely unknown. X-linked dystonia-parkinsonism (XDP) is a …

Importance Despite recessive inheritance, X-linked dystonia-parkinsonism (Lubag disease)
has also been described in women presenting with a late-onset isolated parkinsonian …

Background Increasing evidence supports an extensive and complex genetic contribution to
PD. Previous genome‐wide association studies (GWAS) have shed light on the genetic …

Parkinson's disease (PD) is the most common cause of neurodegenerative movement
disorder and the second most common cause of dementia. Genes are thought to have a …

X-linked recessive dystonia-parkinsonism is a rare movement disorder that is highly
prevalent in Panay Island in the Philippines. Earlier studies identified seven different genetic …

The underlying relation between Parkinson's disease (PD) etiopathology and its major risk
factor, aging, is largely unknown. In light of the causative link between genome stability and …

Objective X‐linked dystonia parkinsonism (XDP) is a neurodegenerative movement disorder
caused by a single mutation: SINE‐VNTR‐Alu (SVA) retrotransposon insertion in TAF1 …

Importance Parkinson disease (PD) is a progressive neurodegenerative disease for which
susceptibility is linked to genetic and environmental risk factors. Objective To identify genetic …

Parkinson's disease is a complex neurodegenerative disorder with a strong genetic
component, for which most known disease-associated variants are single nucleotide …