Thiazolidinediones (TZDs) are a group of diabetes medications currently being investigated
for anti-arthritis effectiveness, one of which is pioglitazone. The purpose of this scoping …

Background Rosiglitazone and pioglitazone are high-affinity peroxisome proliferator-
activated receptor (PPAR)-γ agonists with potent anti-diabetic properties and potential anti …

The aim of the present study was to evaluate the effect of combined treatment of pioglitazone
(PGZ) and prednisolone (PDL) on the progression of adjuvant-induced arthritis in rats …

Objective Preclinical studies suggest that thiazolidinediones (TZDs) may have a protective
effect on rheumatoid arthritis (RA), but evidence from population‐based studies is scarce …

Background: The aims of this study were to assess the anti-degenerative effects of
pioglitazone and to compare these effects with those of methylprednisolone and hyaluronic …

Aim A previous study revealed that PPARγ agonists have anti‐inflammatory effects in
rheumatoid arthritis (RA). Furthermore, some studies have shown that type 2 diabetes …

Aims Osteoarthritis (OA) is the most common musculoskeletal condition in the elderly
population. However, no disease modifying drug exists for this disease. In vivo animal …

The promising role of thiazolidin-4-ones (TZOs) against inflammatory conditions has been
reported. From our lab, one of the TZO derivatives, compound 4C, exerted anti-inflammatory …

Objective To investigate the effect of pentoxifylline (PTX) and pioglitazone (Pg), each alone
and in combination with methotrexate (MTX), on rheumatoid arthritis (RA) induced …

Introduction Temporomandibular-joint osteoarthritis (TMJOA) management is a major
challenge. Minimally invasive therapies (based mainly on injections) have been developed …