Microglia, as phagocytes and antigen-presenting cells in the central nervous system, are
activated in such disease processes as stroke and multiple sclerosis. Because peripheral …

An endogenous cannabimimetic molecule, 2-arachidonoylglycerol, induces a rapid,
transient increase in intracellular free Ca 2+ concentrations in NG108–15 cells through a …

The cannabinoid system is known to be important in neuronal regulation, but is also capable
of modulating immune function. Although the CNS resident microglial cells have been …

Endocannabinoids are important regulators of neurotransmission and, acting on activated
microglia, they are postulated as neuroprotective agents. Endocannabinoid action is …

The endocannabinoid system is involved in the regulation of many physiological effects in
the central and peripheral nervous system. Recent findings have demonstrated the …

Accumulating evidence supports the role of astrocytes in endocannabinoid mediated
modulation of neural activity. It has been reported that some astrocytes express the …

2-Arachidonoylglycerol is an endogenous ligand for the cannabinoid receptors (CB1 and
CB2) and has been shown to exhibit a variety of cannabimimetic activities in vitro and in …

In an earlier study, we reported that chronic ethanol (EtOH) stimulates the formation of
anandamide in human SK-N-SH cells. In the present study, we investigated the effect of …

Endocannabinoids have recently emerged as instructive cues in the developing central
nervous system, and, based on the expression of their receptors, we identified …

Two types of cannabinoid receptor have been cloned and characterized. Whereas CB 1
receptors are ubiquitously expressed in neurons of the CNS, CB 2 receptors have been …