The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo

S Bellocchio, C Montagnoli, S Bozza… - The Journal of …, 2004 - journals.aai.org
In vitro studies have indicated the importance of Toll-like receptor (TLR) signaling in
response to the fungal pathogens Candida albicans and Aspergillus fumigatus. However …

[HTML][HTML] Interactions of Toll-like receptors with fungi

SM Levitz - Microbes and Infection, 2004 - Elsevier
The role of Toll-like receptors (TLRs) in signaling immune responses to fungal pathogens is
reviewed. TLR2 and TLR4, acting via the adapter protein MyD88, signal responses to …

Toll-like receptors as key mediators in innate antifungal immunity

A Roeder, CJ Kirschning, RA Rupec, M Schaller… - Medical …, 2004 - Taylor & Francis
The Toll protein of Drosophila is a transmembrane receptor involved in dorso-ventral
polarization during embryonic development and recognition of infection. In mammals, Toll …

Recognition of fungal pathogens by Toll-like receptors

MG Netea, JWM Van der Meer, BJ Kullberg - Immunology of Fungal …, 2007 - Springer
Toll-like receptors (TLRs) have been identified as a major class of pattern-recognition
receptors. Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, either …

Toll-like receptors and innate antifungal responses

A Roeder, CJ Kirschning, RA Rupec, M Schaller… - Trends in …, 2004 - cell.com
The mammalian Toll-like receptors (TLRs) are homologues of Drosophila Toll and constitute
a novel protein family involved in the mediation of innate immunity and the activation of …

Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells

MG Netea, R Sutmuller, C Hermann… - The Journal of …, 2004 - journals.aai.org
Abstract Toll-like receptor (TLR) 2 and TLR4 play a pivotal role in recognition of Candida
albicans. We demonstrate that TLR2−/− mice are more resistant to disseminated Candida …

Recognition of fungal pathogens by toll-like receptors

MG Netea, G Ferwerda… - Current …, 2006 - ingentaconnect.com
Toll-like receptors (TLRs) have been identified as a major class of pattern-recognition
receptors. Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, either …

[HTML][HTML] Toll-like receptor-2 is essential in murine defenses against Candida albicans infections

E Villamón, D Gozalbo, P Roig, JE O'Connor… - Microbes and …, 2004 - Elsevier
In this work, we studied the role of toll-like receptor-2 (TLR2) in murine defenses against
Candida albicans. TLR2-deficient mice experimentally infected intraperitoneally (ip) or …

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

MG Netea, F Van De Veerdonk… - FEMS Immunology & …, 2008 - academic.oup.com
Abstract Toll-like receptor-1 (TLR1) and TLR6 are receptors of the TLR family that form
heterodimers with TLR2. The role of TLR1 and TLR6 for the recognition of the fungal …

Biological importance of the two Toll-like receptors, TLR2 and TLR4, in macrophage response to infection with Candida albicans

E Blasi, A Mucci, R Neglia, F Pezzini… - FEMS Immunology & …, 2005 - academic.oup.com
The aim of this study was to assess the role of TLR2, TLR4 and MyD88 accessory molecule
in the effector and secretory response of macrophages to viable microbial agents. Using …