Cytokine Signaling Regulates the Outcome of Intracellular Macrophage Parasitism by Cryptococcus neoformans

K Voelz, DA Lammas, RC May - Infection and immunity, 2009 - Am Soc Microbiol
The pathogenic yeast Cryptococcus neoformans and C. gattii commonly cause severe
infections of the central nervous system in patients with impaired immunity but also …

Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages

M Alvarez, A Casadevall - BMC immunology, 2007 - Springer
Background The interaction between macrophages and Cryptococcus neoformans (Cn) is
critical for containing dissemination of this pathogenic yeast. However, Cn can either lyse …

Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome

CM Leopold Wager, CR Hole, KL Wozniak… - Frontiers in …, 2016 - frontiersin.org
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus neoformans host adaptation: toward biological evidence of dormancy

A Alanio, F Vernel-Pauillac, A Sturny-Leclère, F Dromer - MBio, 2015 - Am Soc Microbiol
Cryptococcosis is an opportunistic infection due to the ubiquitous yeast Cryptococcus
neoformans. This yeast interacts closely with innate immune cells, leading to various fates …

Role of CD4+ T cells in a protective immune response against Cryptococcus neoformans in the central nervous system

WC Uicker, JP McCracken, KL Buchanan - Sabouraudia, 2006 - academic.oup.com
Cryptococcosis is a life-threatening disease caused by the encapsulated yeast,
Cryptococcus neoformans. Although infection with C. neoformans is initiated in the lungs …

Cryptococcal infection and Th1-Th2 cytokine balance

Y Koguchi, K Kawakami - International reviews of immunology, 2002 - Taylor & Francis
Cytokines have been recognized as key factors in determining host resistance to infectious
pathogens. In particular, Th1-Th2 cytokine balance in hosts is profoundly associated with the …

Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent …

P Angkasekwinai, N Sringkarin, O Supasorn… - Infection and …, 2014 - Am Soc Microbiol
Cryptococcal infections are primarily caused by two related fungal species: Cryptococcus
neoformans and Cryptococcus gattii. It is well known that C. neoformans generally affects …

Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages

M Alvarez, A Casadevall - Current Biology, 2006 - cell.com
Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …