Single-cell transcriptomic profile of satellite glial cells in trigeminal ganglion

Y Chu, S Jia, K Xu, Q Liu, L Mai, J Liu, W Fan… - Frontiers in Molecular …, 2023 - frontiersin.org
Satellite glial cells (SGCs) play an important role in regulating the function of trigeminal
ganglion (TG) neurons. Multiple mediators are involved in the bidirectional communication …

Diversity of satellite glia in sympathetic and sensory ganglia

AA Mapps, MB Thomsen, E Boehm, H Zhao, S Hattar… - Cell reports, 2022 - cell.com
Satellite glia are the major glial type found in sympathetic and sensory ganglia in the
peripheral nervous system, and specifically, contact neuronal cell bodies. Sympathetic and …

Decoding gene expression signatures in mice trigeminal ganglion across trigeminal neuropathic pain stages via high-throughput sequencing

FF Xu, LC Kong, DL Cao, BX Ding, Q Wu, YC Ding… - Brain Research …, 2022 - Elsevier
Trigeminal neuropathic pain (TNP) arises due to peripheral nerve injury, the mechanisms
underlying which are little known. The altered gene expression profile in sensory ganglia is …

Neuron-interacting satellite glial cells in human trigeminal ganglia have an APC phenotype

M van Velzen, JD Laman, A KleinJan… - The Journal of …, 2009 - journals.aai.org
Satellite glial cells (SGC) in sensory ganglia tightly envelop the neuronal cell body to form
discrete anatomical units. This type of glial cell is considered neuroectoderm-derived and …

Characterization of rat primary trigeminal satellite glial cells and associated extracellular vesicles under normal and inflammatory conditions

HSH Vinterhøj, A Stensballe, M Duroux, P Gazerani - Journal of proteomics, 2019 - Elsevier
Satellite glial cells (SGCs) in sensory ganglia contribute to the pathogenesis of chronic pain,
potentially through mediating extracellular or paracrine signaling. Recently, extracellular …

Changes in the transcriptional fingerprint of satellite glial cells following peripheral nerve injury

SE Jager, LT Pallesen, M Richner, P Harley, Z Hore… - Glia, 2020 - Wiley Online Library
Satellite glial cells (SGCs) are homeostatic cells enveloping the somata of peripheral
sensory and autonomic neurons. A wide variety of neuronal stressors trigger activation of …

Transcriptional profiles of non-neuronal and immune cells in mouse trigeminal ganglia

J Mecklenburg, SA Shein, M Malmir… - Frontiers in Pain …, 2023 - frontiersin.org
Non-neuronal cells constitute 90%–95% of sensory ganglia. These cells, especially glial
and immune cells, play critical roles in the modulation of sensory neurons. This study aimed …

New insights on the role of satellite glial cells

J Lu, D Wang, J Xu, H Zhang, W Yu - Stem Cell Reviews and Reports, 2023 - Springer
Satellite glial cells (SGCs) that surround sensory neurons in the peripheral nervous system
ganglia originate from neural crest cells. Although several studies have focused on SGCs …

Phenotypic changes in satellite glial cells in cultured trigeminal ganglia

V Belzer, N Shraer, M Hanani - Neuron glia biology, 2010 - cambridge.org
Satellite glial cells (SGCs) are specialized cells that form a tight sheath around neurons in
sensory ganglia. In recent years, there is increasing interest in SGCs and they have been …

Single-cell RNA sequencing reveals distinct transcriptional features of the purinergic signaling in mouse trigeminal ganglion

S Jia, JY Liu, Y Chu, Q Liu, L Mai… - Frontiers in Molecular …, 2022 - frontiersin.org
Trigeminal ganglion (TG) is the first station of sensory pathways in the orofacial region. The
TG neurons communicate with satellite glial cells (SGCs), macrophages and other cells …