Alternating sequences of future and past behavior encoded within hippocampal theta oscillations

M Wang, DJ Foster, BE Pfeiffer - Science, 2020 - science.org
Neural networks display the ability to transform forward-ordered activity patterns into reverse-
ordered, retrospective sequences. The mechanisms underlying this transformation remain …

Reversed theta sequences of hippocampal cell assemblies during backward travel

A Cei, G Girardeau, C Drieu, KE Kanbi… - Nature neuroscience, 2014 - nature.com
Hippocampal cell assemblies coding for past, present and future events form theta-timescale
(∼ 100 ms) sequences that represent spatio-temporal episodes. However, the underlying …

Dissociation between the experience-dependent development of hippocampal theta sequences and single-trial phase precession

T Feng, D Silva, DJ Foster - Journal of Neuroscience, 2015 - Soc Neuroscience
Theta sequences are circuit-level activity patterns produced when groups of hippocampal
place cells fire in sequences that reflect a compressed behavioral order of place fields within …

Functionally distinct high and low theta oscillations in the human hippocampus

A Goyal, J Miller, SE Qasim, AJ Watrous… - Nature …, 2020 - nature.com
Based on rodent models, researchers have theorized that the hippocampus supports
episodic memory and navigation via the theta oscillation, a~ 4–10 Hz rhythm that …

Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation

L Kunz, L Wang, D Lachner-Piza, H Zhang… - Science …, 2019 - science.org
Humans are adept in simultaneously following multiple goals, but the neural mechanisms for
maintaining specific goals and distinguishing them from other goals are incompletely …

Self-generated theta oscillations in the hippocampus

R Goutagny, J Jackson, S Williams - Nature neuroscience, 2009 - nature.com
Hippocampal theta rhythm is crucial for spatial memory and is thought to be generated by
extrinsic inputs. In contrast, using a complete rat hippocampus in vitro, we found several …

Coherent coding of spatial position mediated by theta oscillations in the hippocampus and prefrontal cortex

MC Zielinski, JD Shin, SP Jadhav - Journal of Neuroscience, 2019 - Soc Neuroscience
Interactions between the hippocampus (area CA1) and prefrontal cortex (PFC) are crucial for
memory-guided behavior. Theta oscillations (∼ 8 Hz) underlie a key physiological …

Hippocampal theta sequences reflect current goals

AM Wikenheiser, AD Redish - Nature neuroscience, 2015 - nature.com
Hippocampal information processing is discretized by oscillations, and the ensemble activity
of place cells is organized into temporal sequences bounded by theta cycles. Theta …

Theta phase–specific codes for two-dimensional position, trajectory and heading in the hippocampus

JR Huxter, TJ Senior, K Allen, J Csicsvari - Nature neuroscience, 2008 - nature.com
Temporal coding is a means of representing information by the time, as opposed to the rate,
at which neurons fire. Evidence of temporal coding in the hippocampus comes from place …

Theta-phase dependent neuronal coding during sequence learning in human single neurons

L Reddy, MW Self, B Zoefel, M Poncet… - Nature …, 2021 - nature.com
The ability to maintain a sequence of items in memory is a fundamental cognitive function. In
the rodent hippocampus, the representation of sequentially organized spatial locations is …