We often assume that the variables of functional and structural brain parameters—such as
synaptic weights, the firing rates of individual neurons, the synchronous discharge of neural …

An essential step toward understanding neural circuits is linking their structure and their
dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical …

The distribution of in vivo average firing rates within local cortical networks has been
reported to be highly skewed and long tailed. The distribution of average single-cell inputs …

The extraordinary diversity of excitatory synapse sizes is commonly attributed to activity-
dependent processes that drive synaptic growth and diminution. Recent studies also point to …

Despite the importance of the discharge frequency in neuronal communication, little is
known about the firing-rate patterns of cortical populations. Using large-scale recordings …

With advances in connectomics, transcriptome and neurophysiological technologies, the
neuroscience of brain-wide neural circuits is poised to take off. A major challenge is to …

Brain function involves the activity of neuronal populations. Much recent effort has been
devoted to measuring the activity of neuronal populations in different parts of the brain under …

The manner in which different distributions of synaptic weights onto cortical neurons shape
their spiking activity remains open. To characterize a homogeneous neuronal population …

The function of cortical networks depends on the collective interplay between neurons and
neuronal populations, which is reflected in the correlation of signals that can be recorded at …

Neuroscientists increasingly analyze the joint activity of multineuron recordings to identify
population-level structures believed to be significant and scientifically novel. Claims of …