Nanocarrier-mediated immunogenic chemotherapy for triple negative breast cancer

Y Liu, N Qiu, L Shen, Q Liu, J Zhang, YY Cheng… - Journal of Controlled …, 2020 - Elsevier
Triple negative breast cancer (TNBC) does not respond to checkpoint blockade
immunotherapy as a result of immunosuppressive tumor microenvironment. To remodel the …

A Dual‐Targeting Liposome Enhances Triple‐Negative Breast Cancer Chemoimmunotherapy through Inducing Immunogenic Cell Death and Inhibiting STAT3 …

K Luo, L Yang, C Yan, Y Zhao, Q Li, X Liu, L Xie, Q Sun… - Small, 2023 - Wiley Online Library
Immunotherapy gains increasing focus in treating triple‐negative breast cancer (TNBC),
while its efficacy is greatly restricted owing to low tumor immunogenicity and …

Detachable liposomes combined immunochemotherapy for enhanced triple-negative breast cancer treatment through reprogramming of tumor-associated …

M Chen, Y Miao, K Qian, X Zhou, L Guo, Y Qiu… - Nano …, 2021 - ACS Publications
Triple-negative breast cancer (TNBC) is an aggressive disease with a high recurrence rate
and poor outcomes in clinic. In this study, inspired by the enriched innate immune cell type …

Live macrophage-delivered doxorubicin-loaded liposomes effectively treat triple-negative breast cancer

L Yang, Y Zhang, Y Zhang, Y Xu, Y Li, Z Xie, H Wang… - ACS …, 2022 - ACS Publications
Triple-negative breast cancer is often aggressive and resistant to various cancer therapies,
especially corresponding targeted drugs. It is shown that targeted delivery of …

Chemo–immunotherapy for chemo-resistance and metastasis of triple-negative breast cancer by combination of iron-oxide nanoparticles and dual-targeting …

H Hu, L Yu, Z Ding, J Ding, Y Hu, Z Yin - Chinese Chemical Letters, 2023 - Elsevier
Triple-negative breast cancer (TNBC) lacks specific regimens for targeted therapy. Repeat
chemotherapy promotes the evolution of TNBC into highly chemo-resistant tumors that …

Immunotherapy for triple-negative breast cancer

Y Cao, C Chen, Y Tao, W Lin, P Wang - Pharmaceutics, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is characterized by extensive tumor heterogeneity at
both the pathologic and molecular levels, particularly accelerated aggressiveness, and …

Engineering macrophage-derived exosomes for targeted chemotherapy of triple-negative breast cancer

S Li, Y Wu, F Ding, J Yang, J Li, X Gao, C Zhang… - Nanoscale, 2020 - pubs.rsc.org
Triple-negative breast cancer (TNBC) is the most metastatic and recurrent subtype of all
breast cancers. Owing to the lack of therapeutic targets, chemotherapy and surgical …

Bio-inspired and smart nanoparticles for triple negative breast cancer microenvironment

M Keihan Shokooh, F Emami, JH Jeong, S Yook - Pharmaceutics, 2021 - mdpi.com
Triple negative breast cancer (TNBC) with poor prognosis and aggressive nature accounts
for 10–20% of all invasive breast cancer (BC) cases and is detected in as much as 15% of …

The programmed site-specific delivery of LY3200882 and PD-L1 siRNA boosts immunotherapy for triple-negative breast cancer by remodeling tumor …

P Zhang, C Qin, N Liu, X Zhou, X Chu, F Lv, Y Gu, L Yin… - Biomaterials, 2022 - Elsevier
Despite the remarkable success of immunotherapies over the past decade, their
effectiveness against triple-negative breast cancer (TNBC) is limited to a small subset of …

Multifunctional liposomes remodeling tumor immune microenvironment for tumor chemoimmunotherapy

X Li, Y Luo, Z Huang, Y Wang, J Wu, S Zhou - Small Methods, 2023 - Wiley Online Library
In the treatment of solid tumors, the complex barriers composed of cancer‐associated
fibroblasts (CAFs) prevent drug delivery and T cells infiltration into tumor tissues. Although …