Investigating the role of the B-cell receptor in mantle cell lymphoma
DA Dutton - 2022 - eprints.soton.ac.uk
Mantle cell lymphoma (MCL) is a mature B-cell lymphoma typically characterised by the
expression of cluster of differentiation 5 (CD5) and at (11; 14) translocation resulting in …
expression of cluster of differentiation 5 (CD5) and at (11; 14) translocation resulting in …
B-cell receptor responsiveness associates with clinical outcome in mantle cell lymphoma: results from single-cell profiling studies
S Gambino - 2023 - iris.univr.it
Mantle cell lymphoma (MCL) is a rare subtype of Non-Hodgkin Lymphoma (NHL)
characterized by a heterogeneous clinical outcome. The interpatient variability is due to …
characterized by a heterogeneous clinical outcome. The interpatient variability is due to …
The role of B cell antigen receptors in mantle cell lymphoma
Mantle cell lymphoma (MCL) is characterized by an aggressive clinical course and
secondary resistance to currently available therapies in most cases. Therefore, despite …
secondary resistance to currently available therapies in most cases. Therefore, despite …
[HTML][HTML] The B cell receptor signaling pathway in mantle cell lymphoma
MI Merolle, M Ahmed, K Nomie, ML Wang - Oncotarget, 2018 - ncbi.nlm.nih.gov
Signal transduction through the constitutively activated B cell receptor (BCR) plays a key
role in the pathogenesis of B-cell tumors by promoting survival and proliferation of malignant …
role in the pathogenesis of B-cell tumors by promoting survival and proliferation of malignant …
Molecular genetic characterization reveals new subsets of mantle cell lymphoma
EF Thelander, R Rosenquist - Leukemia & lymphoma, 2008 - Taylor & Francis
Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy, which is believed to
originate from naïve B-cells in the mantle zone of lymph nodes. Recently, a more diverse …
originate from naïve B-cells in the mantle zone of lymph nodes. Recently, a more diverse …
B-cell receptor signaling activity identifies patients with mantle cell lymphoma at higher risk of progression
S Gambino, FM Quaglia, M Galasso, C Cavallini… - Scientific Reports, 2024 - nature.com
Mantle cell lymphoma (MCL) is an incurable B-cell malignancy characterized by a high
clinical variability. Therefore, there is a critical need to define parameters that identify high …
clinical variability. Therefore, there is a critical need to define parameters that identify high …
Concomitant high expression of Toll‐like receptor (TLR) and B‐cell receptor (BCR) signalling molecules has clinical implications in mantle cell lymphoma
A Akhter, L Street, S Ghosh, BF Burns… - Hematological …, 2017 - Wiley Online Library
Mantle cell lymphoma (MCL) is an aggressive disease with frequent relapse. Targeted
therapies against B‐cell receptor (BCR) molecules have demonstrated improved outcomes …
therapies against B‐cell receptor (BCR) molecules have demonstrated improved outcomes …
[HTML][HTML] Potentiated B-cell antigen receptor signaling in mantle cell lymphoma is associated with overexpression of surface CD79B and IgM
Background Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin's lymphoma (NHL)
and represents one of the most challenging lymphoma types to treat. The B-cell antigen …
and represents one of the most challenging lymphoma types to treat. The B-cell antigen …
Advances in the understanding of mantle cell lymphoma
P Jares, E Campo - British journal of haematology, 2008 - Wiley Online Library
Mantle cell lymphoma (MCL) is a well‐defined lymphoid neoplasm characterized by a
proliferation of mature B lymphocytes expressing CD5 that may show a spectrum of …
proliferation of mature B lymphocytes expressing CD5 that may show a spectrum of …
Update on the molecular pathogenesis and targeted approaches of mantle cell lymphoma: summary of the 12th annual conference of the European Mantle Cell …
M Dreyling, V Amador, M Callanan… - Leukemia & …, 2015 - Taylor & Francis
Mantle cell lymphoma (MCL) is a distinct subtype of malignant lymphoma which is
characterized by the chromosomal translocation t (11; 14)(q13; q32) resulting in …
characterized by the chromosomal translocation t (11; 14)(q13; q32) resulting in …