The role of gastrointestinal hormones in the regulation of appetite is reviewed. The
gastrointestinal tract is the largest endocrine organ in the body. Gut hormones function to …

Obesity is the main cause of premature death in the UK. Worldwide its prevalence is
accelerating. It has been hypothesized that a gut nutriment sensor signals to appetite …

Peptide hormones released from the gastrointestinal tract communicate information about
the current state of energy balance to the brain. These hormones regulate appetite and …

Many peptides are synthesized and released from the gastrointestinal tract. Although their
roles in the regulation of gastrointestinal function have been known for some time, it is now …

The World Health Organisation has estimated that by 2015 approximately 2.3 billion adults
will be overweight and more than 700 million obese. Obesity is associated with an increased …

The control of food intake consists of neural and hormonal signals between the gut and
central nervous system (CNS). Gut hormones such as CCK, PYY and PP signal to important …

Obesity is one of the greatest threats to the health of the developed world. In order to design
effective drugs to treat the alarming increase in obesity, it is essential to understand the …

Gut hormones signal to the central nervous system to influence energy homeostasis.
Evidence supports the existence of a system in the gut that senses the presence of food in …

The gastrointestinal tract is the largest endocrine organ in the body. It secretes more than 20
different peptide hormones, which serve both a local regulatory function and provide a …

The landmark discovery by Bayliss and Starling in 1902 of the first hormone, secretin,
emerged from earlier observations that a response (pancreatic secretion) following a …