The amygdala is a limbic brain region that plays a key role in emotional processing,
neuropsychiatric disorders, and the emotional‐affective dimension of pain. Preclinical and …

A limbic brain area, the amygdala plays a key role in emotional responses and affective
states and disorders such as learned fear, anxiety, and depression. The amygdala has also …

Cognitive deficits such as impaired decision-making can be a consequence of persistent
pain. Normal functions of the intact amygdala and prefrontal cortex are required for emotion …

A reciprocal relationship exists between persistent pain and negative affective states such
as fear, anxiety, and depression. Accumulating evidence points to the amygdala as an …

An important but not well-understood issue in pain research is the possibly different
mechanisms of acute and chronic types of pain. Increasing evidence suggests that chronic …

The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …

The amygdala is important for processing emotion, including negative emotion such as
anxiety and depression induced by chronic pain. Although remarkable progress has been …

Pain and emotion are strongly regulated by neurons in the central nucleus of the amygdala
(CeA), a major output of the limbic system; yet, the neuronal signaling pathways underlying …

The amygdala, a small deep brain structure involved in behavioral processing through
interactions with other brain regions, has garnered increased attention in recent years in …

The amygdala has been implicated in fundamental functions for the survival of the organism,
such as fear and pain. In accord with this, several studies have shown increased amygdala …