Epileptiform spikes are used to localize epileptogenic brain tissue. The mechanisms that
spontaneously trigger epileptiform discharges are not yet elucidated. Pathological fast ripple …

Summary Objective Ripples (80–150 Hz) recorded from clinical macroelectrodes have been
shown to be an accurate biomarker of epileptogenic brain tissue. We investigated coupling …

Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …

Fast ripples are high-frequency, 250–600Hz field potential oscillations which can be
recorded from hippocampal or neocortical structures. In the neocortex, fast ripples occur …

The interest of epileptologists has recently shifted from the macroscopic analysis of interictal
spikes and seizures to the microscopic analysis of short events in the EEG that are not …

Objective The distinction of hypersynchronous (HYP) and low-voltage fast (LVF) onset
seizures in mesial temporal lobe epilepsy (MTLE) is well established, but classifying …

Objective Differentiating pathologic and physiologic high‐frequency oscillations (HFO s) is
challenging. In patients with focal epilepsy, HFO s occur during the transitional periods …

The neuronal circuit disturbances that drive inter-ictal and ictal epileptiform discharges
remain elusive. Using a combination of extra-operative macro-electrode and micro-electrode …

High-frequency oscillations in local field potentials recorded with intracranial EEG are
putative biomarkers of seizure onset zones in epileptic brain. However, localized 80–500 Hz …

Objective Spontaneous high frequency oscillations (HFOs; ripples 80–250 Hz, fast ripples
(FRs) 250–500 Hz) are biomarkers for epileptogenic tissue in focal epilepsy. Single pulse …