Background: A recently published randomized controlled trial compared single-dose
psilocybin with single-dose niacin in conjunction with psychotherapy in participants with …

Recent randomized controlled trials of psilocybin-assisted psychotherapy for patients with
cancer suggest that this treatment results in large-magnitude reductions in anxiety and …

Background: Clinically significant anxiety and depression are common in patients with
cancer, and are associated with poor psychiatric and medical outcomes. Historical and …

A growing body of evidence shows that existential and spiritual well-being in cancer patients
is associated with better medical outcomes, improved quality of life, and serves as a buffer …

Cancer patients often develop chronic, clinically significant symptoms of depression and
anxiety. Previous studies suggest that psilocybin may decrease depression and anxiety in …

The psychological mechanisms of action involved in psilocybin-assisted psychotherapy are
not yet well understood. Despite a resurgence of quantitative research regarding psilocybin …

Objective: To explore the safety and efficacy of psilocybin in patients with advanced-stage
cancer and reactive anxiety. Design: A double-blind, placebo-controlled study of patients …

Background While psychedelics have been shown to improve psycho-spiritual well-being,
the underlying elements of this change are not well-characterized. The NIH-HEALS posits …

This chapter will review the potential of a treatment approach that uses psilocybin, a novel
psychoactive drug, to ameliorate the psychospiritual distress and demoralization that often …

People with advanced cancer are at heightened risk of desire for hastened death (DHD),
suicidal ideation (SI), and completed suicide. Loss of Meaning (LoM), a component of …