Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with l-NAME-induced hypertension

S Nakmareong, U Kukongviriyapan… - Naunyn-Schmiedeberg's …, 2011 - Springer
Inhibition of nitric oxide synthesis with N ω-nitro-l-arginine methyl ester (l-NAME) induces
marked hypertension and oxidative stress. Curcumin (CUR) has been shown strong …

[HTML][HTML] Hexahydrocurcumin ameliorates hypertensive and vascular remodeling in L-NAME-induced rats

L Panthiya, J Tocharus, A Onsa-Ard… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Hexahydrocurcumin (HHC), a major metabolite of curcumin, possesses several biological
activities such as antioxidant, anti-inflammation, and cardioprotective properties. This study …

Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency

S Nakmareong, U Kukongviriyapan… - Hypertension …, 2012 - nature.com
Tetrahydrocurcumin (THC), a major metabolite of curcumin, possesses strong antioxidant
and cardioprotective properties. However, the activities of THC in hypertension and its …

Curcumin improves endothelial dysfunction and vascular remodeling in 2K-1C hypertensive rats by raising nitric oxide availability and reducing oxidative stress

O Boonla, U Kukongviriyapan, P Pakdeechote… - Nitric Oxide, 2014 - Elsevier
Oxidative stress plays a role in maintaining high arterial blood pressure and contributes to
the vascular changes that lead to hypertension. Consumption of polyphenol-rich foods has …

Quercetin restores plasma nitrite and nitroso species levels in renovascular hypertension

MF Montenegro, EM Neto-Neves… - Naunyn-Schmiedeberg's …, 2010 - Springer
Quercetin has antioxidants properties which may increase nitric oxide (NO) bioavailability.
However, the effects of quercetin on NO status have been poorly studied. We evaluated …

Time-dependent changes in antioxidant enzymes and vascular reactivity of aorta in streptozotocin-induced diabetic rats treated with curcumin

JB Majithiya, R Balaraman - Journal of cardiovascular …, 2005 - journals.lww.com
In the present study changes in oxidative stress and vascular reactivity in aortic rings of
chronic streptozotocin-diabetic (STZ-CON) and nondiabetic (ND-CON) rats is studied at 4 …

Effects of chronic quercetin treatment in experimental renovascular hypertension

MF García-Saura, M Galisteo, IC Villar… - Molecular and cellular …, 2005 - Springer
The aims of the present study were to analyse the effects of an oral daily dose (10 mg/kg) of
the dietary flavonoid quercetin for five weeks in two-kidney, one-clip (2K1C) Goldblatt (GB) …

Antihypertensive effect of quercetin in rats fed with a high-fat high-sucrose diet

Y Yamamoto, E Oue - Bioscience, biotechnology, and biochemistry, 2006 - jstage.jst.go.jp
The effects of different levels of quercetin on the blood pressure were studied in 6-week-old
male Sprague-Dawley rats. The rats were fed with a control diet or a high-fat high-sucrose …

Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats

J Duarte, R Jiménez, F O'Valle, M Galisteo… - Journal of …, 2002 - journals.lww.com
Objectives The present study analysed, for the first time, the effects of the flavonoid quercetin
in rats after chronic inhibition of nitric oxide (NO) synthesis with N ω-nitro-l-arginine methyl …

Curcumin mitigates hypertension, endothelial dysfunction and oxidative stress in rats with chronic exposure to lead and cadmium

A Tubsakul, W Sangartit, P Pakdeechote… - The Tohoku Journal of …, 2021 - jstage.jst.go.jp
Abstract Lead (Pb) and cadmium (Cd) are environmental pollutants and nonessential
elements in the body. Both metals induce the development of hypertension which is …