NetMHCpan, a method for MHC class I binding prediction beyond humans
Binding of peptides to major histocompatibility complex (MHC) molecules is the single most
selective step in the recognition of pathogens by the cellular immune system. The human …
selective step in the recognition of pathogens by the cellular immune system. The human …
NetMHCpan, a Method for Quantitative Predictions of Peptide Binding to Any HLA-A and -B Locus Protein of Known Sequence
Background Binding of peptides to Major Histocompatibility Complex (MHC) molecules is
the single most selective step in the recognition of pathogens by the cellular immune system …
the single most selective step in the recognition of pathogens by the cellular immune system …
Improved methods for predicting peptide binding affinity to MHC class II molecules
Major histocompatibility complex class II (MHC‐II) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, which …
of professional antigen‐presenting cells where they display peptides to T helper cells, which …
MHCflurry: open-source class I MHC binding affinity prediction
TJ O'Donnell, A Rubinsteyn, M Bonsack, AB Riemer… - Cell systems, 2018 - cell.com
Predicting the binding affinity of major histocompatibility complex I (MHC I) proteins and their
peptide ligands is important for vaccine design. We introduce an open-source package for …
peptide ligands is important for vaccine design. We introduce an open-source package for …
A community resource benchmarking predictions of peptide binding to MHC-I molecules
Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules
by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a …
by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a …
NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ
Major histocompatibility complex class II (MHCII) molecules play an important role in cell-
mediated immunity. They present specific peptides derived from endosomal proteins for …
mediated immunity. They present specific peptides derived from endosomal proteins for …
[HTML][HTML] Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule
M Rasmussen, M Harndahl, A Stryhn… - The Journal of …, 2014 - journals.aai.org
Abstract MHC class I molecules (HLA-I in humans) present peptides derived from
endogenous proteins to CTLs. Whereas the peptide-binding specificities of HLA-A and-B …
endogenous proteins to CTLs. Whereas the peptide-binding specificities of HLA-A and-B …
NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets
M Nielsen, M Andreatta - Genome medicine, 2016 - Springer
Background Binding of peptides to MHC class I molecules (MHC-I) is essential for antigen
presentation to cytotoxic T-cells. Results Here, we demonstrate how a simple alignment step …
presentation to cytotoxic T-cells. Results Here, we demonstrate how a simple alignment step …
Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes
W Zhao, X Sher - PLoS computational biology, 2018 - journals.plos.org
A number of machine learning-based predictors have been developed for identifying
immunogenic T-cell epitopes based on major histocompatibility complex (MHC) class I and II …
immunogenic T-cell epitopes based on major histocompatibility complex (MHC) class I and II …
NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8–11
C Lundegaard, K Lamberth, M Harndahl… - Nucleic acids …, 2008 - academic.oup.com
Abstract NetMHC-3.0 is trained on a large number of quantitative peptide data using both
affinity data from the Immune Epitope Database and Analysis Resource (IEDB) and elution …
affinity data from the Immune Epitope Database and Analysis Resource (IEDB) and elution …