Repetitive isolation of known compounds remains a major challenge in natural-product-
based drug discovery. LC-MS/MS-based molecular networking has become a highly …

Three new cyclic peptides including a cyclic tetrapeptide (1), an aspochracin-type cyclic
tripeptide sclerotiotide L (2) and a diketopiperazine dimer (3), have been isolated from the …

A challenging problem in natural product discovery is to rapidly dereplicate known
compounds and expose novel ones from complicated components. Herein, integrating the …

Three new rare cyclopiane diterpenes (1–3), together with thirteen known compounds (4–
16), were isolated and identified from a sea sediment-derived fungus Penicillium sp. TJ403 …

Violaceotides B–E (1–4), four new cyclic tetrapeptides, along with seven known compounds,
were identified from the sponge-associated Aspergillus insulicola IMB18-072 co-cultivated …

Sour rot, caused by Geotrichum citri-aurantii, is a major postharvest disease in citrus and
results in significant economic losses. The genus Beauveria is recognized as a promising …

Under the guidance of MS/MS-based molecular networking, four new cycloheptapeptides,
namely, asperheptatides A–D (1–4), were isolated together with three known analogues …

Despite low temperatures, poor nutrient levels and high pressure, microorganisms thrive in
deep-sea environments of polar regions. The adaptability to such extreme environments …

Marine-derived fungi are a promising and untapped reservoir for discovering structurally
interesting and pharmacologically active natural products. In our efforts to identify novel …

A novel cyclic dipeptide, 14-hydroxy-cyclopeptine (1), was purified from a deep sea derived
fungal isolate identified as an Aspergillus sp. The structure was elucidated by detailed …