Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent

R Invernizzi, J Barnett, B Rawal, A Nair… - European …, 2020 - Eur Respiratory Soc
Increasing bacterial burden in the lower airways of patients with idiopathic pulmonary
fibrosis confers an increased risk of disease progression and mortality. However, it remains …

[HTML][HTML] The lung microbiome in idiopathic pulmonary fibrosis. What does it mean and what should we do about it?

A Morris, K Gibson, RG Collman - American Journal of Respiratory …, 2014 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive lung disease. Despite years
of investigation, the cause of IPF remains enigmatic. The disease is likely multifactorial, with …

Host–microbial interactions in idiopathic pulmonary fibrosis

PL Molyneaux, SAG Willis-Owen, MJ Cox… - American journal of …, 2017 - atsjournals.org
Rationale: Changes in the respiratory microbiome are associated with disease progression
in idiopathic pulmonary fibrosis (IPF). The role of the host response to the respiratory …

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis

PL Molyneaux, MJ Cox, SAG Willis-Owen… - American journal of …, 2014 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown
cause that leads to respiratory failure and death within 5 years of diagnosis. Overt …

[HTML][HTML] Changes in the respiratory microbiome during acute exacerbations of idiopathic pulmonary fibrosis

PL Molyneaux, MJ Cox, AU Wells, HC Kim, W Ji… - Respiratory …, 2017 - Springer
Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) have been defined as events
of clinically significant respiratory deterioration with an unidentifiable cause. They carry a …

Mechanisms of pulmonary fibrosis: conference summary

RM Strieter - Chest, 2001 - journal.chestnet.org
1 Katzenstein ALA, Myers JL. Idiopathic pulmonary fibrosis: clinical relevance of pathologic
classification. Am J Respir Crit Care Med 1998; 157: 1301–1315 2 Travis WD, Matsui K …

Pathognomonic remodeling of blood and lymphatic capillaries in idiopathic pulmonary fibrosis

M Ebina - Respiratory investigation, 2017 - Elsevier
Numerous studies have been published investigating the pathologic alterations in various
interstitial pneumonias, particularly in idiopathic pulmonary fibrosis (IPF). However, the few …

[HTML][HTML] Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis

Y Takahashi, A Saito, H Chiba, K Kuronuma… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is the most frequent and severe form of
idiopathic interstitial pneumonias. Although IPF has not been thought to be associated with …

[HTML][HTML] The role of the lung's microbiome in the pathogenesis and progression of idiopathic pulmonary fibrosis

P Spagnolo, PL Molyneaux, N Bernardinello… - International journal of …, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease that commonly affects older adults and is associated with the histopathological …

Organizing pneumonia and lymphoplasmacytic inflammation predict treatment response in idiopathic pulmonary fibrosis

HR Collard, CD Cool, KO Leslie… - …, 2007 - Wiley Online Library
Aims: To identify individual histopathological features within usual interstitial pneumonia
pattern that predict responsiveness to immunosuppressive therapy. Methods and results …