[HTML][HTML] Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids

AQ Khan, K Rashid, AA AlAmodi, MV Agha… - Biomedicine & …, 2021 - Elsevier
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of
human diseases including cancer. In this line, now it has become evident that ROS …

Role of phytochemicals in perturbation of redox homeostasis in cancer

S Gaikwad, SK Srivastava - Antioxidants, 2021 - mdpi.com
Over the past few decades, research on reactive oxygen species (ROS) has revealed their
critical role in the initiation and progression of cancer by virtue of various transcription …

Oxidative stress inducers in cancer therapy: Preclinical and clinical evidence

ZN Nizami, HE Aburawi, A Semlali, K Muhammad… - Antioxidants, 2023 - mdpi.com
Reactive oxygen species (ROS) are metabolic byproducts that regulate various cellular
processes. However, at high levels, ROS induce oxidative stress, which in turn can trigger …

ROS‐mediated cancer cell killing through dietary phytochemicals

S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …

[HTML][HTML] Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms

H Slika, H Mansour, N Wehbe, SA Nasser… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Reactive oxygen species mediated apoptotic death of colon cancer cells: Therapeutic potential of plant derived alkaloids

VK Nelson, MV Nuli, J Mastanaiah… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the most deaths causing diseases worldwide. Several risk
factors including hormones like insulin and insulin like growth factors (eg, IGF-1) have been …

Targeting reactive oxygen species in cancer via Chinese herbal medicine

Q Qian, W Chen, Y Cao, Q Cao, Y Cui… - … Medicine and Cellular …, 2019 - Wiley Online Library
Recently, reactive oxygen species (ROS), a class of highly bioactive molecules, have been
extensively studied in cancers. Cancer cells typically exhibit higher levels of basal ROS than …

Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways

S Chirumbolo, G Bjørklund, R Lysiuk, A Vella… - International journal of …, 2018 - mdpi.com
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …

Oxidative Stress Modulation and ROS‐Mediated Toxicity in Cancer: A Review on In Vitro Models for Plant‐Derived Compounds

MJ Vallejo, L Salazar, M Grijalva - Oxidative Medicine and …, 2017 - Wiley Online Library
Medicinal and aromatic plants (MAPs) are known and have been long in use for a variety of
health and cosmetics applications. Potential pharmacological usages that take advantage of …