Background Inflammasome-mediated neuroinflammation plays an important role in the
pathogenesis of early brain injury (EBI) following subarachnoid hemorrhage (SAH). The …

Background The NLRP3 inflammasome is a multiprotein complex that regulates the innate
immune inflammatory response by activating caspase-1 and subsequent IL-1β and IL-18 …

Background Nucleotide-binding oligomerization domain-like receptor pyrin domain-
containing protein 3 (NLRP3) plays an important role in mediating inflammatory responses …

Previous studies have demonstrated resveratrol (RSV) has beneficial effects in early brain
injury (EBI) after subarachnoid hemorrhage (SAH). However, the beneficial effects of RSV …

Mounting evidence has suggested that modulating microglia polarization from pro-
inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic …

Background Survivors of sepsis must often endure significant cognitive and behavioral
impairments after discharge, but research on the relevant mechanisms and interventions …

Background Neuroinflammation and blood coagulation responses in cerebrospinal fluid
(CSF) contribute to the poor outcome associated with subarachnoid haemorrhage (SAH) …

Neuroinflammation contributes to the pathogenesis of early brain injury (EBI) after
subarachnoid hemorrhage (SAH). Cytotoxic events following SAH, such as extracellular …

Background The poor prognosis of subarachnoid hemorrhage (SAH) is often attributed to
neuroinflammation. The cGAS-STING axis, a cytoplasmic pathway responsible for detecting …

Background Neuroinflammation is closely associated with the poor prognosis in
subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of …