Macrophage migration inhibitory factor limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling

M Chatterjee, O Borst, B Walker, A Fotinos… - Circulation …, 2014 - Am Heart Assoc
Rationale: Macrophage migration inhibitory factor (MIF) is released on platelet activation.
Circulating MIF could potentially regulate platelets and thereby platelet-mediated …

Platelet-derived MIF: a novel platelet chemokine with distinct recruitment properties

TH Wirtz, S Tillmann, T Strüßmann, S Kraemer… - Atherosclerosis, 2015 - Elsevier
Objective Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine with
chemokine-like functions that plays a role in several inflammatory diseases including …

Platelets are a previously unrecognised source of MIF

T Strüßmann, S Tillmann, T Wirtz… - Thrombosis and …, 2013 - thieme-connect.com
Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine with chemokine-
like functions and a role in atherogenesis. MIF is secreted by various cells including …

Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial …

EA Liehn, I Kanzler, S Konschalla, A Kroh… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—Here, we aimed to clarify the role of CXC chemokine receptor (CXCR) 2 in
macrophage migration-inhibitory factor (MIF)–mediated effects after myocardial ischemia …

MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling

C Klasen, K Ohl, M Sternkopf, I Shachar… - The Journal of …, 2014 - journals.aai.org
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with chemokine-
like functions that plays a pivotal role in the pathogenesis of inflammatory diseases by …

Macrophage migration inhibitory factor: a noncanonical chemokine important in atherosclerosis

H Noels, J Bernhagen, C Weber - Trends in cardiovascular medicine, 2009 - Elsevier
In the recent years, atherogenesis has increasingly been linked to inflammatory processes
in the injured vessel wall. Recruitment and arrest of monocytes, T cells, and neutrophils via …

[HTML][HTML] Macrophage migration inhibitory factor (MIF)-based therapeutic concepts in atherosclerosis and inflammation

D Sinitski, C Kontos, C Krammer… - Thrombosis and …, 2019 - thieme-connect.com
Chemokines orchestrate leukocyte recruitment in atherosclerosis and their blockade is a
promising anti-atherosclerotic strategy, but few chemokine-based approaches have …

[HTML][HTML] Macrophage migration inhibitory factor promotes cardiac stem cell proliferation and endothelial differentiation through the activation of the PI3K/Akt/mTOR and …

J Cui, F Zhang, Y Wang, J Liu… - International …, 2016 - spandidos-publications.com
Macrophage migration inhibitory factor (MIF) has pleiotropic immune functions in a number
of inflammatory diseases. Recent evidence from expression and functional studies has …

Macrophage migration inhibitory factor promotes renal injury induced by ischemic reperfusion

JH Li, Y Tang, J Lv, XH Wang, H Yang… - Journal of Cellular …, 2019 - Wiley Online Library
Macrophage migration inhibitory factor (MIF) is pleiotropic cytokine that has multiple effects
in many inflammatory and immune diseases. This study reveals a potential role of MIF in …

Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells

L Schindler, L Zwissler, C Krammer… - Journal of Leukocyte …, 2021 - academic.oup.com
The chemokine-like inflammatory cytokine macrophage migration inhibitory factor (MIF) is a
pivotal driver of acute and chronic inflammatory conditions, cardiovascular disease …