COVID-19 in the context of inborn errors of immunity: a case series of 31 patients from Mexico

LM Castano-Jaramillo… - Journal of clinical …, 2021 - Springer
Introduction Patients with inborn errors of immunity (IEI) have a compromised or
inappropriate immune response. Although they might be considered a high-risk group for …

[HTML][HTML] Coronavirus disease 2019 in patients with inborn errors of immunity: an international study

I Meyts, G Bucciol, I Quinti, B Neven, A Fischer… - Journal of Allergy and …, 2021 - Elsevier
Background There is uncertainty about the impact of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI) …

Outcome of SARS-CoV-2 infection in 121 patients with inborn errors of immunity: a cross-sectional study

ES Goudouris, F Pinto-Mariz, LO Mendonca… - Journal of clinical …, 2021 - Springer
Purpose There is still scarce data on SARS-CoV-2 infection in patients with Inborn Errors of
Immunity (IEI) and many unresolved questions. We aimed to describe the clinical outcome of …

COVID-19 and inborn errors of immunity

OM Delmonte, R Castagnoli, LD Notarangelo - Physiology, 2022 - journals.physiology.org
Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune
host defense and immunoregulation. Considering the predisposition to develop severe and …

Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19

H Abolhassani, S Delavari, N Landegren… - Journal of Allergy and …, 2022 - Elsevier
Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …

Clinical management of patients with primary immunodeficiencies during the COVID-19 pandemic

I Quinti, I Mezzaroma, C Milito - Expert Review of Clinical …, 2021 - Taylor & Francis
ABSTRACT Introduction: Patients affected by Inborn Errors of Immunity (IEI) represent a
potential group-at-risk in the current COVID-19 pandemic. Studies on large and small …

Coronavirus disease 2019 in patients with inborn errors of immunity: lessons learned

G Bucciol, SG Tangye, I Meyts - Current opinion in pediatrics, 2021 - journals.lww.com
We review the characteristics of SARS-CoV-2 infection in a large number of patients with IEI.
Overall, we found that combined immunodeficiencies, immune dysregulation disorders, and …

Risk factors for severe COVID-19 and hospital admission in patients with inborn errors of immunity-results from a multicenter nationwide study

T Milota, M Sobotkova, J Smetanova… - Frontiers in …, 2022 - frontiersin.org
Despite the progress in the understanding how COVID-19 infection may impact
immunocompromised patients, the data on inborn errors of immunity (IEI) remain limited and …

Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity

C Milito, V Lougaris, G Giardino… - The Journal of …, 2021 - jaci-inpractice.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients with
inborn errors of immunity (IEI) showed a similar infection-fatality rate, a lower incidence in …

Adverse COVID‐19 outcomes in immune deficiencies: Inequality exists between subclasses

E Karakoc Aydiner, S Bilgic Eltan, R Babayeva… - Allergy, 2022 - Wiley Online Library
Background Genetic deficiencies of immune system, referred to as inborn errors of immunity
(IEI), serve as a valuable model to study human immune responses. In a multicenter …