The past two decades reveal a growing role of continuum biomechanics in understanding
homeostasis, adaptation, and disease progression in soft tissues. In this paper, we briefly …

There is substantial evidence that growth and remodeling of load bearing soft biological
tissues is to a large extent controlled by mechanical factors. Mechanical homeostasis, which …

Soft tissues account for a major fraction of the body volume and mass. They are present in
all non-skeletal organs, being responsible for protecting the body, maintaining internal …

The material properties of multipotent mesenchymal tissue change dramatically during the
differentiation process associated with skeletal regeneration. Using a mechanobiological …

Modelling and simulation in mechanobiology play an increasingly important role to unravel
the complex mechanisms that allow resident cells to sense and respond to mechanical cues …

Living soft tissues appear to promote the development and maintenance of a preferred
mechanical state within a defined tolerance around a so-called set point. This phenomenon …

The cells and tissues of the human body are constantly exposed to exogenous and
endogenous forces that are referred to as biomechanical cues. They guide and impact …

Viscoelasticity and its alteration in time and space has turned out to act as a key element in
fundamental biological processes in living systems, such as morphogenesis and motility …

The central paradigm of skeletal mechanobiology is that mechanical forces modulate
morphological and structural fitness of the skeletal tissues—bone, cartilage, ligament and …

Mature tissues can often adapt to changes in their chemical, mechanical, or thermal
environment. For example, in response to sustained increases or decreases in mechanical …