The role of arsenic in obesity and diabetes

T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
As many individuals worlwide are exposed to arsenic, it is necessary to unravel the role of
arsenic in the risk of obesity and diabetes. Therefore, the present study reviewed the effects …

Role of arsenic exposure in adipose tissue dysfunction and its possible implication in diabetes pathophysiology

K Renu, H Madhyastha, R Madhyastha, M Maruyama… - Toxicology letters, 2018 - Elsevier
Exposure to arsenic in drinking water can stimulate a diverse number of diseases that
originate from impaired lipid metabolism in adipose and glucose metabolism, leading to …

Effects of arsenic on adipocyte metabolism: Is arsenic an obesogen?

ZA Ceja-Galicia, A Daniel, AM Salazar, P Pánico… - Molecular and cellular …, 2017 - Elsevier
The environmental obesogen model proposes that in addition to a high-calorie diet and
diminished physical activity, other factors such as environmental pollutants and chemicals …

The potential biological mechanisms of arsenic-induced diabetes mellitus

CH Tseng - Toxicology and applied pharmacology, 2004 - Elsevier
Although epidemiologic studies carried out in Taiwan, Bangladesh, and Sweden have
demonstrated a diabetogenic effect of arsenic, the mechanisms remain unclear and require …

[HTML][HTML] Arsenic-induced abnormalities in glucose metabolism: Biochemical basis and potential therapeutic and nutritional interventions

A Kulshrestha, U Jarouliya, G Prasad… - World Journal of …, 2014 - wjgnet.com
Health hazards due to the consumption of heavy metals such as arsenic have become a
worldwide problem. Metabolism of arsenic produces various intermediates which are more …

Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response

Y Hou, P Xue, CG Woods, X Wang, J Fu… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: There is growing evidence that chronic exposure to inorganic arsenic (iAs) is
associated with an increased prevalence of type 2 diabetes (T2D). However, the …

Metabolic derangement by Arsenic: a review of the mechanisms

K Bibha, TM Akhigbe, MA Hamed… - Biological Trace Element …, 2024 - Springer
Studies have implicated arsenic exposure in various pathological conditions, including
metabolic disorders, which have become a global phenomenon, affecting developed …

Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiologic evidence

A Navas-Acien, EK Silbergeld… - Environmental …, 2006 - ehp.niehs.nih.gov
Chronic arsenic exposure has been suggested to contribute to diabetes development. We
performed a systematic review of the experimental and epidemiologic evidence on the …

A state-of-the-science review of arsenic's effects on glucose homeostasis in experimental models

F Castriota, L Rieswijk, S Dahlberg… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: The prevalence of type 2 diabetes (T2D) has more than doubled since 1980.
Poor nutrition, sedentary lifestyle, and obesity are among the primary risk factors. While an …

Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid

DS Paul, AW Harmon, V Devesa… - Environmental …, 2007 - ehp.niehs.nih.gov
Background Increased prevalences of diabetes mellitus have been reported among
individuals chronically exposed to inorganic arsenic (iAs). However, the mechanisms …