Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses
The most frequent fetal birth defect associated with prenatal Zika virus (ZIKV) infection is
brain calcification, which in turn may potentially affect neurological development in infants …
brain calcification, which in turn may potentially affect neurological development in infants …
Zika virus induces abnormal cranial osteogenesis by negatively affecting cranial neural crest development
Zika virus (ZIKV) infection during gestation is deemed to be coupled to birth defects through
direct impairment of the nervous system during neurogenesis. However, in this study, our …
direct impairment of the nervous system during neurogenesis. However, in this study, our …
Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome
RS Aguiar, F Pohl, GL Morais, FCS Nogueira… - Science …, 2020 - science.org
Zika virus (ZIKV) infection during pregnancy can cause a set of severe abnormalities in the
fetus known as congenital Zika syndrome (CZS). Experiments with animal models and in …
fetus known as congenital Zika syndrome (CZS). Experiments with animal models and in …
Stress-induced unfolded protein response contributes to Zika virus–associated microcephaly
I Gladwyn-Ng, L Cordón-Barris, C Alfano… - Nature …, 2018 - nature.com
Accumulating evidence support a causal link between Zika virus (ZIKV) infection during
gestation and congenital microcephaly. However, the mechanism of ZIKV-associated …
gestation and congenital microcephaly. However, the mechanism of ZIKV-associated …
Zika virus cell tropism in the developing human brain and inhibition by azithromycin
H Retallack, E Di Lullo, C Arias… - Proceedings of the …, 2016 - National Acad Sciences
The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …
Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage
Zika virus (ZIKV) infection of pregnant women can result in fetal brain abnormalities. It has
been established that ZIKV disrupts neural progenitor cells (NPCs) and leads to embryonic …
been established that ZIKV disrupts neural progenitor cells (NPCs) and leads to embryonic …
Fibroblast growth factor 2 enhances Zika virus infection in human fetal brain
Zika virus (ZIKV) is an emerging pathogen that can cause microcephaly and other
neurological defects in developing fetuses. The cellular response to ZIKV in the fetal brain is …
neurological defects in developing fetuses. The cellular response to ZIKV in the fetal brain is …
Zika virus infection perturbs osteoblast function
N Mumtaz, M Koedam, PB van den Doel… - Scientific Reports, 2018 - nature.com
Zika virus (ZIKV) infection is typically characterized by a mild self-limiting disease presenting
with fever, rash, myalgia and arthralgia and severe fetal complications during pregnancy …
with fever, rash, myalgia and arthralgia and severe fetal complications during pregnancy …
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target
Z He, S An, J Chen, S Zhang, C Tan… - Proceedings of the …, 2020 - National Acad Sciences
Mounting evidence has associated Zika virus (ZIKV) infection with congenital malformations,
including microcephaly, which raises global alarm. Nonetheless, mechanisms by which …
including microcephaly, which raises global alarm. Nonetheless, mechanisms by which …
Zika virus in the human placenta and developing brain: cell tropism and drug inhibition
H Retallack, E Di Lullo, C Arias, KA Knopp… - BioRxiv, 2016 - biorxiv.org
The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …