Reactive oxygen species (ROS) and antioxidants as immunomodulators in exercise: implications for heme oxygenase and bilirubin
DT Thomas, NR DelCimmuto, KD Flack, DE Stec… - Antioxidants, 2022 - mdpi.com
Exercise is commonly prescribed as a lifestyle treatment for chronic metabolic diseases as it
functions as an insulin sensitizer, cardio-protectant, and essential lifestyle tool for effective …
functions as an insulin sensitizer, cardio-protectant, and essential lifestyle tool for effective …
Serum bilirubin levels in overweight and obese individuals: the importance of anti-inflammatory and antioxidant responses
L Žiberna, Z Jenko-Pražnikar, A Petelin - Antioxidants, 2021 - mdpi.com
Obesity is a chronic condition involving low-grade inflammation and increased oxidative
stress; thus, obese and overweight people have lower values of serum bilirubin. Essentially …
stress; thus, obese and overweight people have lower values of serum bilirubin. Essentially …
Rats genetically selected for high aerobic exercise capacity have elevated plasma bilirubin by upregulation of hepatic biliverdin reductase-A (BVRA) and suppression …
TD Hinds Jr, JF Creeden, DM Gordon, AC Spegele… - Antioxidants, 2020 - mdpi.com
Exercise in humans and animals increases plasma bilirubin levels, but the mechanism by
which this occurs is unknown. In the present study, we utilized rats genetically selected for …
which this occurs is unknown. In the present study, we utilized rats genetically selected for …
Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
R Takei, T Inoue, N Sonoda, M Kohjima, M Okamoto… - PloS one, 2019 - journals.plos.org
Objective Although previous studies have reported a negative relationship between serum
bilirubin concentration and the development of diabetes mellitus (DM), the relationship …
bilirubin concentration and the development of diabetes mellitus (DM), the relationship …
[HTML][HTML] The effect of different doses of aerobic exercise training on total bilirubin levels
Low serum bilirubin levels have been associated with increased risk for cardiovascular
disease, and recent data suggest that lower body fat and reductions in weight are …
disease, and recent data suggest that lower body fat and reductions in weight are …
Bilirubin as an important physiological modulator of oxidative stress and chronic inflammation in metabolic syndrome and diabetes: a new aspect on old molecule
T Inoguchi, N Sonoda, Y Maeda - Diabetology international, 2016 - Springer
Bilirubin belongs to the superfamily of tetrapyrrolic compounds, which is one of the most
highly conserved groups of molecules. These compounds have evoked to have pluripotent …
highly conserved groups of molecules. These compounds have evoked to have pluripotent …
Obesity-related oxidative stress: the impact of physical activity and diet manipulation
Obesity-related oxidative stress, the imbalance between pro-oxidants and antioxidants (eg,
nitric oxide), has been linked to metabolic and cardiovascular disease, including endothelial …
nitric oxide), has been linked to metabolic and cardiovascular disease, including endothelial …
Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation
Obesity-induced endoplasmic reticulum (ER) stress causes chronic inflammation in adipose
tissue and steatosis in the liver, and eventually leads to insulin resistance and type 2 …
tissue and steatosis in the liver, and eventually leads to insulin resistance and type 2 …
Redox mechanism of reactive oxygen species in exercise
F He, J Li, Z Liu, CC Chuang, W Yang, L Zuo - Frontiers in physiology, 2016 - frontiersin.org
It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …
[HTML][HTML] Reactive oxygen species in exercise and insulin resistance: Working towards personalized antioxidant treatment
Reactive oxygen species (ROS) are well known for their role in insulin resistance and the
development of cardiometabolic disease including type 2 diabetes mellitus (T2D) …
development of cardiometabolic disease including type 2 diabetes mellitus (T2D) …