Microsatellite instability is a well‐recognised phenomenon. Ten to 15% of sporadic
colorectal cancers with a high level of MSI form a well defined group with distinct …

Abstract About 10–15% of colorectal cancers show high-level microsatellite instability. The
characteristics and very existence of low-level instability (MSI-L) are unclear, although some …

Twelve to 16% of colorectal cancers (CRCs) display a high degree of microsatellite
instability (MSI-H), whereas most are believed to be microsatellite stable (MSS). The …

In one third of colorectal cancer patients, tumours occur in the rectum. Unique aetiologies
may underlie the increased carcinogenesis in this region of the colorectum. Microsatellite …

BACKGROUND: 10% of sporadic colorectal cancers are characterised by a low level of
microsatellite instability (MSI-L). These are not thought to differ substantially from …

Abstract In December 1997, the National Cancer Institute sponsored “The International
Workshop on Microsatellite Instability and RER Phenotypes in Cancer Detection and …

Frequent microsatellite instability MSI (MSI-H) occurring in human tumors is characterized by
defective DNA mismatch repair and unique clinical features. However, infrequent MSI (MSI …

Introduction Colorectal cancer is a heterogeneous tumor type with regard to molecular
pathogenesis and genetic instability. The majority of colorectal cancers display …

Recent studies have demonstrated the presence of microsatellite instability (MSI) in tumors
from patients with hereditary nonpolyposis colorectal cancer and in a large number of …

This study assessed whether low‐level microsatellite instability (MSI‐L) is a phenomenon
specific to colorectal cancers or is also present in other tumour types. Breast (grade III ductal …