In this study, we hypothesized that anti-parkinsonian effect of puerarin is attributable to its
antioxidant properties via Nrf2-dependent glutathione (GSH) biosynthesis mechanism …

Puerarin, an active component of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep
is well‐known for its anti‐oxidative and neuroprotective activities. Although anti‐Parkinson's …

Recently, combination therapy has proven to be an effective strategy for treating polygenic/
multifactorial/complex disorder such as Parkinson's disease (PD). Here, we hypothesized …

Background. Progesterone receptor (PR) modulates neuroprotective and regenerative
responses in Parkinson's disease and related neurological diseases. Objectives. The …

It has been acknowledged that oxidative stress, resulting in the apoptosis of dopaminergic
neurons, is a key mechanism in the pathogenesis of Parkinson's disease (PD). Puerarin …

The aim of the present study was to assess the neuroprotective effects of pinostrobin (PSB),
a dietary bioflavonoid, and its underlying mechanisms in neurotoxin-induced Parkinson's …

Baicalein, a major bioactive flavone constituent isolated from Scutellaria baicalensis Georgi,
has neuroprotective properties in several neurological disorders. Many studies suggest that …

Parkinson's disease (PD) is a neurodegenerative disorder closely associated with oxidative
stress. The biochemical and cellular alterations that occur after cell and mouse treatment …

Pramipexole (PPX) is a common drug for the treatment of Parkinson's disease. However, the
mechanism allows PPX in the progression of Parkinson's disease remains largely unknown …

Parkinson's disease (PD) is neurodegenerative disease, featured by a loss of dopaminergic
neurons in the substantia nigra pars compacta (SNpc), characteristic motor symptoms and …