The Impact of Long Noncoding RNAs in Tissue Regeneration and Senescence

J Tavares e Silva, J Pessoa, S Nóbrega-Pereira… - Cells, 2024 - mdpi.com
Overcoming senescence with tissue engineering has a promising impact on multiple
diseases. Here, we provide an overview of recent studies in which cellular senescence was …

Role of lncRNAs in cellular aging

U Degirmenci, S Lei - Frontiers in endocrinology, 2016 - frontiersin.org
Aging is a universal, intrinsic, and time-dependent biological decay that is linked to intricate
cellular processes including cellular senescence, telomere shortening, stem cell exhaustion …

Role of lncRNAs in aging and age‐related diseases

J He, C Tu, Y Liu - Aging Medicine, 2018 - Wiley Online Library
Aging is progressive physiological degeneration and consequently declined function, which
is linked to senescence on both cellular and organ levels. Accumulating studies indicate that …

LncRNAs regulating stemness in aging

A Sousa‐Franco, K Rebelo, ST da Rocha… - Aging …, 2019 - Wiley Online Library
One of the most outstanding observations from next‐generation sequencing approaches
was that only 1.5% of our genes code for proteins. The biggest part is transcribed but give …

Non-coding RNAs steering the senescence-related progress, properties, and application of mesenchymal stem cells

J Cai, H Qi, K Yao, Y Yao, D Jing, W Liao… - Frontiers in Cell and …, 2021 - frontiersin.org
The thirst to postpone and even reverse aging progress has never been quenched after all
these decades. Unequivocally, mesenchymal stem cells (MSCs), with extraordinary abilities …

[HTML][HTML] Roles of long noncoding RNAs in aging and aging complications

L Jin, Q Song, W Zhang, B Geng, J Cai - Biochimica et Biophysica Acta …, 2019 - Elsevier
Aging is a universal and time dependent complex biological process, characterized by a
progressive physiological dysfunction and an increased vulnerability to death. Though the …

LncRNAs regulatory networks in cellular senescence

PK Puvvula - International journal of molecular sciences, 2019 - mdpi.com
Long noncoding RNAs (lncRNAs) are a class of transcripts longer than 200 nucleotides with
no open reading frame. They play a key role in the regulation of cellular processes such as …

Long non‐coding RNA s in aging organs and tissues

W Xing, W Gao, G Mao, J Zhang, X Lv… - Clinical and …, 2017 - Wiley Online Library
The aging process directly impacts bodily functions on multiple levels, including a reduced
ability to resist stress, damage and disease. Besides changes in metabolic control, the aging …

[HTML][HTML] Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging

I Grammatikakis, AC Panda, K Abdelmohsen… - Aging (Albany …, 2014 - ncbi.nlm.nih.gov
During aging, progressive deleterious changes increase the risk of disease and death.
Prominent molecular hallmarks of aging are genomic instability, telomere attrition …

Noncoding RNA Contribution to Aging and Lifespan

AP Ugalde, D Roiz-Valle… - The Journals of …, 2024 - academic.oup.com
Aging is a multifactorial process characterized by an age-related decline in organismal
fitness. This deterioration is the major risk factor for chronic diseases such as cardiovascular …