Objective Gastric cancer is a major gastrointestinal malignancy for which targeted therapies
are emerging as treatment options. This study sought to identify the most prevalent …

Background. Gastric cancer (GC) is a major global cancer burden and the second most
common cause of global cancer-related deaths. The addition of anti-ERBB2 (HER2) …

Background In advanced gastric cancer (AGC), most clinical trials are designed on the basis
of protein expression or gene amplification of specific genes. Recently, next-generation …

Gastric cancer (GC) is one of the most common malignancies and remains the second
leading cause of cancer-related death worldwide. There is an increasing understanding of …

Background Intertumoral heterogeneity represents a significant hurdle to identifying
optimized targeted therapies in gastric cancer (GC). To realize precision medicine for GC …

Background Gastric cancer (GC) is a leading cause of cancer deaths, and an increased
number of GC patients adopt to next-generation sequencing (NGS) to identify tumor …

A more detailed understanding of the somatic genetic events that drive gastrointestinal
adenocarcinomas is necessary to improve diagnosis and therapy. Using data from high …

Advancement in the field of cancer genomics is revolutionizing the molecular
characterization of a wide variety of different cancers. Recent application of large-scale, next …

Gastric cancer is a heterogeneous disease with diverse molecular and histological
subtypes. We performed whole-genome sequencing in 100 tumor-normal pairs, along with …

Background: Gastric cancer (GC) is a leading cause of cancer deaths worldwide. Since the
approval of trastuzumab, targeted therapies are emerging as promising treatment options for …