T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

[HTML][HTML] T cells in atherosclerosis: key players in the pathogenesis of vascular disease

H Hinkley, DA Counts, E VonCanon, M Lacy - Cells, 2023 - mdpi.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipid-
rich plaques within arterial walls. T cells play a pivotal role in the pathogenesis of …

Protective and pathogenic roles of CD8+ T cells in atherosclerosis

C Cochain, A Zernecke - Basic research in cardiology, 2016 - Springer
Although infiltration of CD8+ T cells in human atherosclerotic lesions has been described 30
years ago, the role of these cells in lesion development has long remained enigmatic. While …

T cells in atherogenesis: for better or for worse?

AKL Robertson, GK Hansson - Arteriosclerosis, thrombosis, and …, 2006 - Am Heart Assoc
The idea that atherosclerosis is an inflammatory disease is no longer controversial. Instead,
much of the current research is now focused on understanding what drives this inflammation …

Mechanisms of disease: the evolving role of regulatory T cells in atherosclerosis

J George - Nature Clinical Practice Cardiovascular Medicine, 2008 - nature.com
Atherosclerosis and related complications still represent the major cause of morbidity and
mortality in the western world. The mechanisms that govern the progression and …

[HTML][HTML] CD8+ T Cells in Atherosclerosis

S Schäfer, A Zernecke - Cells, 2020 - mdpi.com
Atherosclerotic lesions are populated by cells of the innate and adaptive immune system,
including CD8+ T cells. The CD8+ T cell infiltrate has recently been characterized in mouse …

[HTML][HTML] The emerging role of Th1 cells in atherosclerosis and its implications for therapy

J Chen, X Xiang, L Nie, X Guo, F Zhang… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis is a chronic progressive inflammatory disease of the large and medium-
sized artery walls. The molecular mechanisms regulating the onset and progression of …

T cells in atherosclerosis

K Tse, H Tse, J Sidney, A Sette… - International immunology, 2013 - academic.oup.com
Atherosclerosis is a chronic inflammatory disease of the artery wall. Atherosclerotic lesions
contain monocytes, macrophages, smooth muscle cells and T lymphocytes. Here, we review …

Regulatory T-cell immunity in atherosclerosis

Z Mallat, H Ait-Oufella, A Tedgui - Trends in Cardiovascular Medicine, 2007 - Elsevier
Atherosclerosis is an inflammatory disease of the arterial wall where both innate and
adaptive T-cell-driven immunoinflammatory responses contribute to disease development …

Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wall

DFJ Ketelhuth, GK Hansson - Thrombosis and haemostasis, 2011 - thieme-connect.com
Atherosclerosis is a chronic inflammatory disease. Atherosclerotic plaques contain abundant
immune cells that can dictate and effect inflammatory responses. Among them, T cells are …