Arp2/3 complex is an actin filament nucleation and branching machinery conserved in all
eukaryotes from yeast to human. Arp2/3 complex branched networks generate pushing …

The Arp2/3 complex polymerizes new actin filaments from the sides of existing filaments,
forming Y-branched networks that are critical for actin-mediated force generation. Binding of …

The Arp2/3 complex is an evolutionary conserved molecular machine that generates
branched actin networks. When activated, the Arp2/3 complex contributes the actin …

Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive
cellular processes such as lamellipodial protrusion and endocytosis. Arp2/3 complex is …

Actin branch junctions are conserved cytoskeletal elements critical for the generation of
protrusive force during actin polymerization-driven cellular motility. Assembly of actin branch …

Branched actin networks have emerged as major force-generating structures driving the
protrusions in various distinct cell types and processes, ranging from lamellipodia operating …

The actin-related protein (Arp) 2/3 complex nucleates branched actin filament networks
pivotal for cell migration, endocytosis and pathogen infection. Its activation is tightly …

The mechanisms regulating the disassembly of branched actin networks formed by the
Arp2/3 complex still remain to be fully elucidated. In addition, the impact of Arp3 isoforms on …

Actin-related protein (Arp) 2/3 complex nucleates branched actin networks that drive cell
motility. It consists of seven proteins, including two actin-related subunits (Arp2 and Arp3) …

Regulation of the Arp2/3 complex is required for productive nucleation of branched actin
networks. An emerging aspect of regulation is the incorporation of subunit isoforms into the …