[HTML][HTML] Advances in single-cell omics and multiomics for high-resolution molecular profiling

J Lim, C Park, M Kim, H Kim, J Kim… - Experimental & Molecular …, 2024 - nature.com
Single-cell omics technologies have revolutionized molecular profiling by providing high-
resolution insights into cellular heterogeneity and complexity. Traditional bulk omics …

Single-cell (multi) omics technologies

L Chappell, AJC Russell, T Voet - Annual review of genomics …, 2018 - annualreviews.org
Single-cell multiomics technologies typically measure multiple types of molecule from the
same individual cell, enabling more profound biological insight than can be inferred by …

[HTML][HTML] The technological landscape and applications of single-cell multi-omics

A Baysoy, Z Bai, R Satija, R Fan - Nature Reviews Molecular Cell …, 2023 - nature.com
Single-cell multi-omics technologies and methods characterize cell states and activities by
simultaneously integrating various single-modality omics methods that profile the …

Progress in single-cell multimodal sequencing and multi-omics data integration

X Wang, X Wu, N Hong, W Jin - Biophysical Reviews, 2024 - Springer
With the rapid advance of single-cell sequencing technology, cell heterogeneity in various
biological processes was dissected at different omics levels. However, single-cell mono …

Computational methods for single-cell omics across modalities

M Efremova, SA Teichmann - Nature methods, 2020 - nature.com
Single-cell omics approaches provide high-resolution data on cellular phenotypes,
developmental dynamics and communication networks in diverse tissues and conditions …

Single-cell omics analyses enabled by microchip technologies

Y Deng, A Finck, R Fan - Annual review of biomedical …, 2019 - annualreviews.org
Single-cell omics studies provide unique information regarding cellular heterogeneity at
various levels of the molecular biology central dogma. This knowledge facilitates a deeper …

[HTML][HTML] Single-cell omics: A new direction for functional genetic research in human diseases and animal models

S Kong, R Li, Y Tian, Y Zhang, Y Lu, Q Ou, P Gao… - Frontiers in …, 2023 - frontiersin.org
Over the past decade, with the development of high-throughput single-cell sequencing
technology, single-cell omics has been emerged as a powerful tool to understand the …

[HTML][HTML] Methods and applications for single-cell and spatial multi-omics

K Vandereyken, A Sifrim, B Thienpont… - Nature Reviews Genetics, 2023 - nature.com
The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome
from single cells is transforming our understanding of cell biology in health and disease. In …

Defining cell identity with single‐cell omics

L Mincarelli, A Lister, J Lipscombe, IC Macaulay - Proteomics, 2018 - Wiley Online Library
Cells are a fundamental unit of life, and the ability to study the phenotypes and behaviors of
individual cells is crucial to understanding the workings of complex biological systems. Cell …

[HTML][HTML] Statistical single cell multi-omics integration

M Colomé-Tatché, FJ Theis - Current Opinion in Systems Biology, 2018 - Elsevier
Single cell high throughput genomic measurements are revolutionizing the fields of biology
and medicine, providing a means to tackle biological problems that have thus far been …